Protein Alignment stau and PRKRA

DIOPT Version :9

• Sequence 1: NP_476751.1
• Gene: stau / 37065
• FlyBaseID: FBgn0003520
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_003681.1
• Gene: PRKRA / 8575
• HGNCID: 9438
• Length: 313
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 101/480 - (21%)
• Similarity: 155/480 - (32%)
• Gaps: 177/480 - (36%)

  Fly   540 LQQAKHDAAARALQVLKTQAISASEEALEDSMDEGDKKSPISQVHEIGIK-RNMTVHFKVLREEG 603
            :.|::|.|.|..|:...:...|     |...:.....|:||..:||.|:| :|:.| ::..|.:.
Human     1 MSQSRHRAEAPPLEREDSGTFS-----LGKMITAKPGKTPIQVLHEYGMKTKNIPV-YECERSDV 59

  Fly   604 PAHMKNFITACIVGSIVTEGEGNGKKVSKKRAAEKMLVELQKLPPLTPTKQTPLKRIKVKTPGKS 668
            ..|:..|.....||.|...|||..||::|.||||..:..|                       |:
Human    60 QIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINIL-----------------------KA 101

  Fly   669 GAAAREGSVVSGTDGPTQTGKPERRKRLNPPKDKLIDMDDADNPITKLIQLQQTRKEKEPIFELI 733
            .|     |:......|..   |:..|:   ||::|       |||..|.:|......:.|.:.|.
Human   102 NA-----SICFAVPDPLM---PDPSKQ---PKNQL-------NPIGSLQELAIHHGWRLPEYTLS 148

  Fly   734 AKNGNETARRREFVMEVSASGSTARGTGNSKKLAKRNAAQALFELLEAVQVTPTNETQSSEECST 798
            .:.|  .|.:||:............|.|.|||.||||||:..  |.:...::|.|....
Human   149 QEGG--PAHKREYTTICRLESFMETGKGASKKQAKRNAAEKF--LAKFSNISPENHISL------ 203

  Fly   799 SATMSAVTAPAVEATAEGKVPMVATPVGPMPGILILRQNKKPAKKRDQIVIVKSNVESKEEEANK 863
                                                                             
Human   204 ----------------------------------------------------------------- 203

  Fly   864 EVAVAAEENSNNSANSGDSSNSSSGDSQATEAASESALNTSTGSNTSGVSSNSSNVGANTDGNNH 928
                                                   |:...::.|.:.:|..       |:.
Human   204 ---------------------------------------TNVVGHSLGCTWHSLR-------NSP 222

  Fly   929 AESKNNTESSSNSTSNTQSAGVHMKEQLL-YLSKLLDFEVNFSDYPKGNHN-EFLTIVTLSTHPP 991
            .|..|..:.|..|..||...      ||| .::|...|.:.:.|..:.:.| ::..:..|||.|.
Human   223 GEKINLLKRSLLSIPNTDYI------QLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPI 281

  Fly   992 QICHGVGKSSEESQNDAASNALKIL 1016
            .:|||.|.|...:|:|||.|||:.|
Human   282 TVCHGSGISCGNAQSDAAHNALQYL 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stau	NP_476751.1	DSRM	312..375	CDD:214634
		DSRM	<529..555	CDD:294045	5/14 (36%)
		DSRM	579..644	CDD:214634	24/65 (37%)
		DSRM	712..780	CDD:214634	22/67 (33%)
		Staufen_C	<953..1020	CDD:293091	24/66 (36%)
PRKRA	NP_003681.1	Sufficient for self-association and interaction with TARBP2	1..103		34/130 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		5/19 (26%)
		DSRM_PRKRA_rpt1	32..102	CDD:380718	27/93 (29%)
		Sufficient for self-association and interaction with TARBP2	102..195		31/114 (27%)
		DSRM_PRKRA_rpt2	126..192	CDD:380720	23/69 (33%)
		Sufficient for self-association and interaction with TARBP2	195..313		36/235 (15%)
		DSRM_PRKRA_rpt3	239..310	CDD:380721	25/74 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810