DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stau and Prkra

DIOPT Version :9

Sequence 1:	NP_476751.1	Gene:	stau / 37065	FlyBaseID:	FBgn0003520	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	NP_001019951.1	Gene:	Prkra / 311130	RGDID:	1306707	Length:	313	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	77/279 - (27%)
Similarity:	121/279 - (43%)	Gaps:	55/279 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 VPTPPSKITLFVGKQKFVGIGRTLQQAKHDAAARALQVLKTQAISASEEALEDSMDEGDKKSPIS 581
            |||...::|  ||.....|.|.:.:.|||.||..|:.:||..|....  |:.|.:.....|.|.:
  Rat    63 VPTFTFRVT--VGDITCTGEGTSKKLAKHRAAEAAINILKANASICF--AVPDPLMPDPSKQPKN 123

  Fly   582 QVHEIGIKRNMTVH-------FKVLREEGPAHMKNFITACIVGSIVTEGEGNGKKVSKKRAAEKM 639
            |::.||..:.:.:|       :.:.:|.||||.:.:.|.|.:.|.:..|:|..||.:|:.||||.
  Rat   124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKF 188

  Fly   640 LVELQKLPPLTPTKQTPLKRIKVKTPGKSGAAAREGSVVSGTDGPT-QTGKPERRKRLNPPKDKL 703
            |.:...:.|......|                    :||..:.|.| .:.:....:::|..|..|
  Rat   189 LAKFSNISPENHISLT--------------------NVVGHSLGCTWHSLRNSPGEKINLLKRSL 233

  Fly   704 IDMDDADNPITKLIQ-LQQTRKEKE------PIFELIAKNGNETARRREFVMEVSASGST-ARGT 760
            :.:     |.|..|| |.:..||:.      .|.||.| ||     :.:.:.|:|.|..| ..|:
  Rat   234 LSL-----PNTDYIQLLSEIAKEQGFSITYLDIEELSA-NG-----QYQCLAELSTSPITVCHGS 287

  Fly   761 ----GNSKKLAKRNAAQAL 775
                ||::..|..||.|.|
  Rat   288 GISCGNAQSDAAHNALQYL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stau	NP_476751.1	DSRM	312..375	CDD:214634
		DSRM	<529..555	CDD:294045	9/25 (36%)
		DSRM	579..644	CDD:214634	23/71 (32%)
		DSRM	712..780	CDD:214634	25/76 (33%)
		Staufen_C	<953..1020	CDD:293091
Prkra	NP_001019951.1	Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	1..103		16/41 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		DSRM	35..100	CDD:214634	14/38 (37%)
		Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	102..195		27/94 (29%)
		DSRM	126..192	CDD:238007	21/65 (32%)
		Sufficient for self-association and interaction with TARBP2. /evidence=ECO:0000250	195..313		34/143 (24%)
		DSRM	241..307	CDD:214634	23/72 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810