DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5098 and si:dkey-94l16.4

DIOPT Version :9

Sequence 1:	NP_001261066.1	Gene:	CG5098 / 37063	FlyBaseID:	FBgn0034300	Length:	1339	Species:	Drosophila melanogaster
Sequence 2:	XP_009304640.1	Gene:	si:dkey-94l16.4 / 101885814	ZFINID:	ZDB-GENE-121214-291	Length:	732	Species:	Danio rerio

Alignment Length:	790	Identity:	158/790 - (20%)
Similarity:	249/790 - (31%)	Gaps:	242/790 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   615 QQDDEPPKNHTSPA--MPPPSPQSNSSSSSSSSSSANTHSSQSSHAVNNIPKPEINNKATTDTPA 677
            :.|.||    |.||  :.|....||::.:.|..|.::..|..|  .|..:|...:.     ...|
Zfish    59 ESDSEP----TIPAGQIQPDEAFSNTTVTLSYVSRSHLFSEHS--PVYGVPSAFLR-----AYDA 112

  Fly   678 SPALVEQGDIDAKPAVSV----HECDE-----EEEPAVNKVSPAHPDPPTTAAVAAPPATESPKK 733
            .....:.||:|....|||    ..|::     .|:...|..:..:...|....:    |.|:.|
Zfish   113 GKLAADAGDVDCVQQVSVPLGLTTCEQLGFLTPEQVVENMAALCYLQQPDVENL----ALETLK- 172

  Fly   734 SSPAANSESCPFGEVEDKLEQMFA-----------GIEEE----TERISSPEKP--------AEE 775
             |..||...|.|....|:|:...|           |..||    .|.:.....|        :||
Zfish   173 -SLQANPGECRFPISVDELQNGAANGLWSVNPFQGGFPEENGGDVEGLHPNVNPELVLLISRSEE 236

  Fly   776 SAAMVAHNLTAQLALDPS--KTLDT--PAENQTSVLAVLAPNQTPTPEIRPVATKAAMKSTMPSP 836
            ...:.....:..|:|:|.  ..||:  |:|.||...:  |.|.||...:...|.:......|.|
Zfish   237 PLILPNEATSFALSLNPEFVSPLDSALPSEEQTQDDS--AQNATPPSGLMNDAMQKEAIEVMNS- 298

  Fly   837 VHSPIPQSRSTSTPLVAGDDSKSNTPVPAKAPAPRRPPPRRLSMGM-------DASLLRF----M 890
             .|.:..::.|.........:..:..:..|....|:..|.|...||       :..|.|.    :
Zfish   299 -SSCVKLTKQTENDASDAFKTSDDLVIKTKKIPERKTLPPRAGRGMRLEAIVQNMQLFRCKSTRV 362

  Fly   891 IDDPPAKKPGRKK-------------KVTKEP-DFEDDDKP----STSAAAAAALAARQLS---- 933
            :......||.|.|             .|..|| :.....:.    |||......|...:..
Zfish   363 VKPRGTNKPSRVKTHNSVLAEKTEVQHVHTEPTEVRRSSRRKATISTSTPVKTFLKCTKNESTNR 427

  Fly   934 EAASATKSKPAAGAKKKNAGVKGKKGSAGKGNAKNAKQNGKKSARKPAFTTDEDSTPAPTNGGGS 998
            ..:|.|.::......|.|..:|           |:.|:..||....|.|:..|
Zfish   428 NCSSLTSNQGNQAVHKHNVSIK-----------KSVKRKNKKCKSTPFFSAQE------------ 469

  Fly   999 VPELRFK--------------SPFILIKPDGSVSIKNTHSAEDVNEKQTKVKKA----------- 1038
             ||:..|              :|::      .|...|.......|||:.|.|.:
Zfish   470 -PEINLKCLKLKKKEVRDDSFAPYV------RVQFSNCTIVNYPNEKRGKSKTSAGFLSGITPAT 527

  Fly  1039 ---PHERKNLRGMHSSTLSNRYDADTTDSTWICVFCKRGPHKLGLGDLFGPYLVTSDCDEYRAAV 1100
               .|.|.::.|.|...|             :|..|....:.:.||||.|||..
Zfish   528 PGFQHGRVSMDGEHQDLL-------------VCCLCGSSSNAMDLGDLHGPYYA----------- 568

  Fly  1101 QTPGAQDIDGMFVNKRRREDMVKGQERNLPAVPATLANIMQAPKI-SMHKRKRKQTHDSSISYSD 1164
                                                .....|.|: |.|:.......|||..
Zfish   569 ------------------------------------EGFKPASKVASNHQEDENSDSDSSFR--- 594

  Fly  1165 DPNESRSQCSSVDLLDCSTESKFVETFRGMGKTSE------------------NGFEVWLHEDCA 1211
              .::.::.:..|.||.        .:.|:|:.:.                  :..|.|.|||||
Zfish   595 --GKTAAEGNWTDSLDW--------RWSGVGEPARRVRTDSPIDWYSPPVVPLHETEHWFHEDCA 649

  Fly  1212 VWSNDIHLIGAHVNGLDAAVWDSTRYQCVLCQQTGASICCFQRCCKAAAHVPCGRSANWSLSEED 1276
            :||..:.|:...:.||:.||..:....|..||:|||::.|..:.|....|..|...:...|:|::
Zfish   650 IWSAGVFLVRGKLYGLENAVKLAKVSVCSTCQRTGATLGCVYKGCLNKYHYTCAVQSGCVLNEDN 714

  Fly  1277 RKVYCHLHRH 1286
            ..:.|..|::
Zfish   715 YSMKCRKHKN 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5098	NP_001261066.1	PHD_SF	1068..1284	CDD:304600	48/234 (21%)
si:dkey-94l16.4	XP_009304640.1	ePHD_RAI1_like	547..722	CDD:277138	48/234 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574403
Domainoid	1	1.000	60	1.000	Domainoid score	I10545
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24577
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14955
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030