DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5757 and dtymk

DIOPT Version :9

Sequence 1:	NP_001261065.1	Gene:	CG5757 / 37062	FlyBaseID:	FBgn0034299	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001032187.1	Gene:	dtymk / 567734	ZFINID:	ZDB-GENE-990603-11	Length:	212	Species:	Danio rerio

Alignment Length:	207	Identity:	90/207 - (43%)
Similarity:	132/207 - (63%)	Gaps:	1/207 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KRGALIIFEGCDRSGKTTQSRLLVELLKSKGIPTLPMNFPERSSSIGQVINSYLTNSKDLPDEVI 69
            :|||||:.||.||:|||||.:.||:.::..|.....|.||:|::.|||:|:|||....:|.|..:
Zfish     4 RRGALIVLEGVDRAGKTTQCQKLVQAIQQSGRAAEIMRFPDRTTKIGQLISSYLEKKSNLEDHTV 68

  Fly    70 HLMFSANRWEHINQVKEKLLEGTTLVVDRYSFSGVAYSAAK-GLDFDWCYAPERGLIKPDAVFYL 133
            ||:|||||||.:..:|:||.||..||||||:|||||:::|| |...:||..|:.||.|||.|.:|
Zfish    69 HLLFSANRWEMVPVMKQKLEEGINLVVDRYAFSGVAFTSAKPGFSLEWCMNPDVGLPKPDLVMFL 133

  Fly   134 RAPPNDLTHRGQYGKERYEKVEFQGRVAEVFNRICSKEGSYFHQFDARQSVEDLHAQIASITEEL 198
            :..||...:||:||.||||...||..|.:.|..:.......:...||.:::|::|..|..::|.:
Zfish   134 QLNPNVAANRGEYGNERYETSAFQRTVQQRFEELMQDTSINWKVIDAARTIEEVHKDIKDLSENI 198

  Fly   199 LPKVATRPLDTL 210
            :.....:|:..|
Zfish   199 ISLAEEQPVGEL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5757	NP_001261065.1	PLN02924	1..197	CDD:178512	87/192 (45%)
CG5757	NP_001261065.1	Thymidylate_kin	12..191	CDD:280400	81/179 (45%)
dtymk	NP_001032187.1	PLN02924	5..211	CDD:178512	90/206 (44%)
dtymk	NP_001032187.1	Thymidylate_kin	11..191	CDD:280400	81/179 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596190
Domainoid	1	1.000	167	1.000	Domainoid score	I3816
eggNOG	1	0.900	-	-		E1_COG0125
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6285
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3932
OMA	1	1.010	-	-		QHG54297
OrthoDB	1	1.010	-	-		D1259751at2759
OrthoFinder	1	1.000	-	-		FOG0003433
OrthoInspector	1	1.000	-	-		oto41206
orthoMCL	1	0.900	-	-		OOG6_100714
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R645
SonicParanoid	1	1.000	-	-		X2795
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.700