DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5757 and Dtymk

DIOPT Version :9

Sequence 1:	NP_001261065.1	Gene:	CG5757 / 37062	FlyBaseID:	FBgn0034299	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001099137.1	Gene:	Dtymk / 21915	MGIID:	108396	Length:	212	Species:	Mus musculus

Alignment Length:	209	Identity:	92/209 - (44%)
Similarity:	132/209 - (63%)	Gaps:	1/209 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AGKRGALIIFEGCDRSGKTTQSRLLVELLKSKGIPTLPMNFPERSSSIGQVINSYLTNSKDLPDE 67
            |.:|||||:.||.||:|||||...||..|.:.|.....:.|||||:.||:::||||....:|.|.
Mouse     2 ASRRGALIVLEGVDRAGKTTQGLKLVTALCASGHRAELLRFPERSTEIGKLLNSYLEKKTELEDH 66

  Fly    68 VIHLMFSANRWEHINQVKEKLLEGTTLVVDRYSFSGVAYSAAK-GLDFDWCYAPERGLIKPDAVF 131
            .:||:|||||||.:..:|.||.:|.|||:|||:|||||::.|| ....|||..|:.||.|||.:.
Mouse    67 SVHLLFSANRWEQVPLIKAKLNQGVTLVLDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLIL 131

  Fly   132 YLRAPPNDLTHRGQYGKERYEKVEFQGRVAEVFNRICSKEGSYFHQFDARQSVEDLHAQIASITE 196
            :|:....|...||::|.||||...||.:|...|.::..::...:...||.:|:|::|.:|.:.:|
Mouse   132 FLQLQLLDAAARGEFGLERYETGTFQKQVLLCFQQLMEEKNLNWKVVDASKSIEEVHKEIRAHSE 196

  Fly   197 ELLPKVATRPLDTL 210
            :.:...|.|||..|
Mouse   197 DAIRNAAQRPLGEL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5757	NP_001261065.1	PLN02924	1..197	CDD:178512	86/194 (44%)
CG5757	NP_001261065.1	Thymidylate_kin	12..191	CDD:280400	79/179 (44%)
Dtymk	NP_001099137.1	PLN02924	5..211	CDD:178512	91/206 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850286
Domainoid	1	1.000	159	1.000	Domainoid score	I4093
eggNOG	1	0.900	-	-		E1_COG0125
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6285
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3980
Isobase	1	0.950	-	0	Normalized mean entropy	S1131
OMA	1	1.010	-	-		QHG54297
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003433
OrthoInspector	1	1.000	-	-		oto95302
orthoMCL	1	0.900	-	-		OOG6_100714
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R645
SonicParanoid	1	1.000	-	-		X2795
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.640