Protein Alignment Muc55B and TIR4

DIOPT Version :10

• Sequence 1: NP_611285.2
• Gene: Muc55B / 37057
• FlyBaseID: FBgn0034294
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_014652.1
• Gene: TIR4 / 854173
• SGDID: S000005535
• Length: 487
• Species: Saccharomyces cerevisiae
• Alignment Length: 443
• Identity: 130/443 - (29%)
• Similarity: 220/443 - (49%)
• Gaps: 97/443 - (21%)

  Fly    39 TLMAAPEA---RDDSTLINDCFNHYLED-QTNVIMGYNLQYTGCLRTAQSG--RDELTKESASER 97
            ||:||..|   ......||: .|..|:| :||:.....|.|     |..||  .|::.
Yeast     7 TLLAALAAIAYAQTQAQINE-LNVVLDDVKTNIADYITLSY-----TPNSGFSLDQMP------- 58

  Fly    98 EALLDRTNKMCSSLTECDTLVDGLEFFDCYRNASSDSYKVMFTLNSDSSLDFNRISAKYQVIETD 162
            ..::|...::.:                   |.|.|||..::     |.:||:.:.....::..
Yeast    59 AGIMDIAAQLVA-------------------NPSDDSYTTLY-----SEVDFSAVEHMLTMVPW- 98

  Fly   163 LTDCVDSARLDYAHDMDACDENLTLCLKGGETSPEPTVPTTTSGTPVTVTTPEAPVSTTPEAPVT 227
                 .|:||  ..:::|.|.:||.......:|.|....:..|.|..:|    ||.|    :.|.
Yeast    99 -----YSSRL--LPELEAMDASLTTSSSAATSSSEVASSSIASSTSSSV----APSS----SEVV 148

  Fly   228 TTPVAPSTTETPVPTTPVAPSTTEAPVST--TPEAPVSTTPVAPSTTEAPVPTTPVAPSTTEAPV 290
            ::.||||::|  |.::.||||::|...|:  :..:.|:::.||||::|  |.::.||.|::|  |
Yeast   149 SSSVAPSSSE--VVSSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSE--VVSSSVASSSSE--V 207

  Fly   291 PTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPST 355
            .::.||||::|  |.::.||||::|  |.::.||.|::|  |.::.||||::|  |.::.||.||
Yeast   208 ASSSVAPSSSE--VVSSSVAPSSSE--VVSSSVASSSSE--VASSSVAPSSSE--VVSSSVASST 264

  Fly   356 TEA----PVPTTPVAPSTTEAPVPTTPV----APSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTT 412
            :||    .|.::....|:||: |.::.|    |.|::|| |.::||:...:.:..|.     |::
Yeast   265 SEATSSSAVTSSSAVSSSTES-VSSSSVSSSSAVSSSEA-VSSSPVSSVVSSSAGPA-----SSS 322

  Fly   413 EAPVPTTPVASSTTEAPVSTTPVAP---STTEAPVSSTPE---STTEAASTTE 459
            .||..:| :|||::.|..|.:.:||   :||..|.||...   ||....:.||
Yeast   323 VAPYNST-IASSSSTAQTSISTIAPYNSTTTTTPASSASSVIISTRNGTTVTE 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc55B	NP_611285.2	DUF725	52..170	CDD:398779	22/120 (18%)
		motB	<138..307	CDD:183756	49/170 (29%)
		rne	<258..447	CDD:236766	70/199 (35%)
TIR4	NP_014652.1	SRP1_TIP1	19..113	CDD:395534	27/138 (20%)