Protein Alignment Muc55B and HKR1

DIOPT Version :10

• Sequence 1: NP_611285.2
• Gene: Muc55B / 37057
• FlyBaseID: FBgn0034294
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_010708.1
• Gene: HKR1 / 852030
• SGDID: S000002828
• Length: 1802
• Species: Saccharomyces cerevisiae
• Alignment Length: 428
• Identity: 132/428 - (30%)
• Similarity: 201/428 - (46%)
• Gaps: 58/428 - (13%)

  Fly    81 TAQSGRDELTKESASEREALLDRTNKMCSSLTECDTLVDG--------LEFFDCYRNASSDSYKV 137
            |:......:::||.:...:.:..||.:.||.:  ||:|..        ......:.:|:|.|..:
Yeast   359 TSSEASQGVSRESNTFAVSSISTTNFIVSSAS--DTVVSTSSTNTVPYSSVHSTFVHATSSSTYI 421

  Fly   138 MFTLNSDSSLDFNRISAKYQVIETDLTDCVDSARLDYAHDMDACDENLTLCLKGGETSP-----E 197
            ..:|.|..||..: :|:.:.|..      ..||.:.::....|.....|.........|     .
Yeast   422 SSSLYSSPSLSAS-VSSHFGVAP------FPSAYISFSSVPVAVSSTYTSSPSASVVVPSAYASS 479

  Fly   198 PTVPTTTSGTPVTVTTPEAPVSTT----PEAPV------TTTPVAP---STTETPVPTTPVAPST 249
            |:||...|.|..:..:..|.:|:|    |.|||      |::|.||   |:|.|..|:.|||.|:
Yeast   480 PSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSS 544

  Fly   250 TEAPVSTTPEAP--VSTT-------PVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVP 305
            |   .:::|.||  :|:|       |||.|:|....|:.|||.|:|....|:.|||.|:|....|
Yeast   545 T---YTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPVAISSTYTSSPSVPVAVSSTYTSSP 606

  Fly   306 TTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTT 370
            :.|.|.|:|....|:.|||.|:|....|:.|.|.|:|....|:.|||.|:|....|:.|.|.|:|
Yeast   607 SAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSVPVAVSSTYTSSPSAPAAISST 671

  Fly   371 EAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVAPSTTEAPVPTTPVASSTT-----EAPV 430
            ....|:.|||.|:|....|:.|.|.|:|....|:.|||.|:|....|:.|.|.|:|     .|||
Yeast   672 YTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPV 736

  Fly   431 ------STTPVAPSTTEAPVSSTPESTTEAASTTERSP 462
                  :::|.||:...:..:|:|.:....:||...||
Yeast   737 AVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSP 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc55B	NP_611285.2	DUF725	52..170	CDD:398779	19/96 (20%)
		motB	<138..307	CDD:183756	59/195 (30%)
		rne	<258..447	CDD:236766	77/208 (37%)
HKR1	NP_010708.1	PHA03307	452..>776	CDD:223039	111/326 (34%)