DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Elk and SKOR

DIOPT Version :9

Sequence 1:	NP_477009.1	Gene:	Elk / 37047	FlyBaseID:	FBgn0011589	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	NP_186934.1	Gene:	SKOR / 821052	AraportID:	AT3G02850	Length:	828	Species:	Arabidopsis thaliana

Alignment Length:	710	Identity:	153/710 - (21%)
Similarity:	293/710 - (41%)	Gaps:	162/710 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 QSIKKSRLILPHYGVFKGIWDWVILVATFYVALMVPYNAAFAKA-DRQTKVSDVIVEALFIVDIL 314
            :.|.:..::.|....:|. |...||:...|.:...|....|.:. .....:.|:..:..|:|||:
plant    67 RDISRGSIVHPDNRWYKA-WTMFILIWALYSSFFTPLEFGFFRGLPENLFILDIAGQIAFLVDIV 130

  Fly   315 LNFRTTFV----SRKGEVVSNSKQIAINYLRGWFALDLLAALPFDHLYASDLYDGEDSHIHLVKL 375
            |.|   ||    ||...::.....||:.||:..|.:||||.:|:|.:|.:   .||...:..:.|
plant   131 LTF---FVAYRDSRTYRMIYKRSSIALRYLKSTFIIDLLACMPWDIIYKA---AGEKEEVRYLLL 189

  Fly   376 TRLLRLARLL---QKIDRYSQHTAMI--LTLLMFSFTLAAHWLACIWYVIAV------KEYEWFP 429
            .||.|:.|::   .|:::..:...:.  :..|:|......|..|||:|.:|.      :.|.|
plant   190 IRLYRVHRVILFFHKMEKDIRINYLFTRIVKLIFVELYCTHTAACIFYYLATTLPASQEGYTW-- 252

  Fly   430 ESNIGWLQL--LAERKNASVAILTTAETYSTALYFTFTSLTSVGFGNVSANTTAEKVFTIIMMLI 492
               ||.|:|  .:..|...:.:.|   .|:|::||...::.:||:|::.|....|.:|.::.:..
plant   253 ---IGSLKLGDYSYSKFREIDLWT---RYTTSMYFAVVTMATVGYGDIHAVNMREMIFAMVYISF 311

  Fly   493 GALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDYFQTSWSLSHGID 557
            ..::.|.:.||:||:|.: .|:...:..|..|:..::..:.:.:.::.:|..:.:..:..|:  .
plant   312 DMILGAYLIGNMTALIVK-GSKTERFRDKMADIMRYMNRNKLGRNIRGQITGHLRLQYESSY--T 373

  Fly   558 IYETLREFPEELRGDVSMHLHREILQ-LPIFEAASQGCLKLLSLHIKTNFCAPGEYLIHKGDALN 621
            ....|::.|..:|..::..|:...:: :|:|...|...:..:.:.:...|..|||.::.:|..::
plant   374 EAAVLQDIPVSIRAKIAQTLYLPYIEKVPLFRGCSSEFINQIVIRLHEEFFLPGEVIMEQGSVVD 438

  Fly   622 YIYYLCNGSME---VIKD--DMVVAILGKGDLVGSDINVHLVATSNGQMTATTNSAGQDVVVRSS 681
            .:|::|:|.:|   :.||  :.:||:|....             |.|:::...| ..|...||
plant   439 QLYFVCHGVLEEIGITKDGSEEIVAVLQPDH-------------SFGEISILCN-IPQPYTVR-- 487

  Fly   682 SDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQ---HD---LTCNLREGYENQ------D 734
                           :..|..:|||   .:|.|.|.::   ||   :..||.||.|:.      :
plant   488 ---------------VAELCRILRL---DKQSFMNILEIFFHDGRRILNNLLEGKESNVRIKQLE 534

  Fly   735 SDIGPSFPLPSISEDDENREEAEEGGKGEKE-------------NGGGPPS-----GASPLHNIS 781
            |||  :|.:        :::|||...|....             ..||.|:     |.||||
plant   535 SDI--TFHI--------SKQEAELALKLNSAAFYGDLYQLKSLIRAGGDPNKTDYDGRSPLH--- 586

  Fly   782 NSPLHATR------------------------SPLLGMGSPRNQR----LHQRGRSL-------- 810
               |.|:|                        :|||......|.|    |.:.|.:|
plant   587 ---LAASRGYEDITLYLIQESVDVNIKDKLGSTPLLEAIKNGNDRVAALLVKEGATLNIENAGTF 648

  Fly   811 ----ITLRETNKRHRTLNAACSLDRGSFEEPEPLEEEQSSGGKRPSLERLDSQVSTLHQD 866
                :...:::...|.|:.....:...::...||....|.|....:::.:::..:.|.:|
plant   649 LCTVVAKGDSDFLKRLLSNGIDPNSKDYDHRTPLHVAASEGFYVLAIQLVEASANVLAKD 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075
		PAS_3	41..129	CDD:285623
		Ion_trans	285..516	CDD:278921	66/248 (27%)
		Ion_trans_2	<455..510	CDD:285168	16/54 (30%)
		Crp	583..>650	CDD:223736	17/72 (24%)
		CAP_ED	586..715	CDD:237999	27/133 (20%)
SKOR	NP_186934.1	PLN03192	70..827	CDD:215625	152/707 (21%)
		ANK repeat	580..611	CDD:293786	8/36 (22%)
		ANK repeat	613..644	CDD:293786	8/30 (27%)
		ANK repeat	677..708	CDD:293786	5/30 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	111	1.000	Domainoid score	I2073
eggNOG	1	0.900	-	-		E1_KOG0498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8395
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810