DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elk and LOC562466

DIOPT Version :9

Sequence 1:	NP_477009.1	Gene:	Elk / 37047	FlyBaseID:	FBgn0011589	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	XP_009295831.2	Gene:	LOC562466 / 562466	-ID:	-	Length:	801	Species:	Danio rerio

Alignment Length:	527	Identity:	104/527 - (19%)
Similarity:	214/527 - (40%)	Gaps:	95/527 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 WDWVILVATFYVALMVPYNAAFAKADRQTK----VSDVIVEALFIVDILLNFRTTFVSRKGEVVS 330
            |..::.:|..|....||...||.....:..    ..|:|.:.::|.|::........|:.|:::.
Zfish   318 WLSMVTIAFNYNLWFVPVRMAFPYHSPEVVPLWFTLDIIADFIYIFDMIFFQPRLQFSKGGDIIY 382

  Fly   331 NSKQIAINYLR-GWFALDLLAALPFDHLYASDLYDGEDSHIHLVKLTRLLRLARLLQKIDR---- 390
            :.:.|...|.. |.|..|::|.||.|.||....::.      :.:|.||:::....:..||
Zfish   383 DREVIKKKYRESGRFQNDVIAVLPIDLLYIPFGFNS------VFRLNRLMKVESFFEFSDRLEGL 441

  Fly   391 ----YSQHTAMILTLLMFSFTLAAHWLACIWYVIAVKEYEWFPESNIGWLQLLAERKNASVAILT 451
                |.......:..|:|    ..|..||::||.:|.:       .||..:.:...|.::
Zfish   442 LTRAYIWRVIRTIGYLLF----ILHLNACLYYVASVSQ-------GIGSTKWVYSGKGSA----- 490

  Fly   452 TAETYSTALYFTFTSLTSVG--------FGNVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAII 508
                |.:..::...||..:.        ||         ::|.:....:|||..:::...:..:|
Zfish   491 ----YLSCFFYAEKSLLMIAELPFPETMFG---------QIFQMTNYFVGALFLSIILAQMRDVI 542

  Fly   509 QRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDYFQTSWSLSHGIDIYETLREFPEELRGDV 573
            ....:.::.:.:.......::..:::||.::.|:..::..:|.....:|..|.|.:.|..:|..:
Zfish   543 GAATAGQTYFRASMDACVAYMVTNHIPKMVQSRVRTWYNYTWDSQGMLDESELLGQMPLVMRTAI 607

  Fly   574 SMHLHREILQ-LPIFEAASQGCLKLLSLHIKTNFCAPGEYLIHKGDALNYIYYLCNGSMEVI--K 635
            ::.::....| :.:|:......|..:.|.:|:....||::::.|||....:|.:..|.::||  .
Zfish   608 AVDINLATFQKIELFKGCDNQMLVDMLLRLKSIVYLPGDFVVKKGDIGKEMYIIKAGEVQVIGGP 672

  Fly   636 DDMVVAILGKGDLVGSDINVHLVATSNGQMTATTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGL 700
            |:.:|.:..|...|..:|:: |.:::||....|.|             :.|..:.:|..:....|
Zfish   673 DNKIVFVTLKAGCVFGEISL-LQSSANGGNRRTAN-------------VAAHGFANLFVLDKKDL 723

  Fly   701 VEVLRLYPEYQQQFANDIQHDLTCNLREGYENQDSDIGPSFPLPSISEDDENREEAEEGGKGEKE 765
            .::|..|||.|:..|           |:|.:.    :....|.|:...|:|.:       ||...
Zfish   724 NDILIHYPESQKVLA-----------RKGRKL----LKAKGPPPAAKADEEKK-------KGLAL 766

  Fly   766 NGGGPPS 772
            .|..||:
Zfish   767 FGQKPPT 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075
		PAS_3	41..129	CDD:285623
		Ion_trans	285..516	CDD:278921	48/251 (19%)
		Ion_trans_2	<455..510	CDD:285168	10/62 (16%)
		Crp	583..>650	CDD:223736	17/69 (25%)
		CAP_ED	586..715	CDD:237999	31/130 (24%)
LOC562466	XP_009295831.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840