Protein Alignment Elk and eag

DIOPT Version :10

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: NP_001036275.1
• Gene: eag / 32428
• FlyBaseID: FBgn0000535
• Length: 1270
• Species: Drosophila melanogaster
• Alignment Length: 1342
• Identity: 402/1342 - (29%)
• Similarity: 603/1342 - (44%)
• Gaps: 311/1342 - (23%)

  Fly     1 MP-ARKGLLAPQNTFLDTIATRFDG-THSNFVLGNAQANGNPIVYCSDGFVDLTGYSRAQIMQKG 63
            || .|:||:|||||||:.|..|.:. ..|:|:|.|||....|||||::.|..::||:||::|||.
  Fly     1 MPGGRRGLVAPQNTFLENIIRRSNSQPDSSFLLANAQIVDFPIVYCNESFCKISGYNRAEVMQKS 65

  Fly    64 CS--CHFLYGPDTKEEHKQQIEKSLSNKMELKLEVIFYKK-----------------EGAPFWCL 109
            |.  |.|:||..|.:|...::|.:|.|:.:.:.|::.|||                 :..|.|.|
  Fly    66 CRYVCGFMYGELTDKETVGRLEYTLENQQQDQFEILLYKKNNLQCGCALSQFGKAQTQETPLWLL 130

  Fly   110 FDIVPIKNEKRDVVLFLASHKDITHTKMLEMNVNEECDSVFALTAALLGARFRAGSNAGMLGLGG 174
            ..:.||:||:..|||||.:.:|||   .|:..::.|                   ...|:|||..
  Fly   131 LQVAPIRNERDLVVLFLLTFRDIT---ALKQPIDSE-------------------DTKGVLGLSK 173

  Fly   175 LPGLGGPAASDGDTEAGEGNNLDVPAGCNMGRRRSRAVLYQLSGHYKPEKGGVKTKLKLGNNFMH 239
            ...|.....                        |||    |.|.|....|...|.     :|..|
  Fly   174 FAKLARSVT------------------------RSR----QFSAHLPTLKDPTKQ-----SNLAH 205

  Fly   240 --STEAP-FPEYKTQSIKKSRLILPHYGVFKGIWDWVILVATFYVALMVPYNAAF---AKADRQT 298
              |..|. .|:|:.::.|....||.||..||.|||||||..|||.|:|||||.||   ...|...
  Fly   206 MMSLSADIMPQYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFKNKTSEDVSL 270

  Fly   299 KVSDVIVEALFIVDILLNFRTTFVSRKGEVVSNSKQIAINYLRGWFALDLLAALPFDHLYASDL- 362
            .|.|.||:.:|.:||:|||.||||...|||||:.|.|.:|||:.||.:|||:.||:|...|.|.
  Fly   271 LVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYLKSWFIIDLLSCLPYDVFNAFDRD 335

  Fly   363 YDGEDSHIHLVKLTRLLRLARLLQKIDRYSQHTAMILTLLMFSFTLAAHWLACIWYVIAVKEYEW 427
            .||..|....:|:.|||||.|:::|:|||.::.|.:|.||:..:.|.|||||||||.|...:
  Fly   336 EDGIGSLFSALKVVRLLRLGRVVRKLDRYLEYGAAMLILLLCFYMLVAHWLACIWYSIGRSD--- 397

  Fly   428 FPESNI--GWLQLLAERKNASVAILTTAET-------------YSTALYFTFTSLTSVGFGNVSA 477
             .::.|  .||..||....:..:.:.:.:|             |.||||||.|.:||||||||:|
  Fly   398 -ADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNGPSRKSMYVTALYFTMTCMTSVGFGNVAA 461

  Fly   478 NTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRI 542
            .|..||||||.||:|.||::|.:||:||.|||:|.|..:.|.....::::|:.||.:||.|.:|:
  Fly   462 ETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKALSERV 526

  Fly   543 EDYFQTSWSLSHGIDIYETLREFPEELRGDVSMHLHREIL-QLPIFEAASQGCLKLLSLHIKTNF 606
            .||..::|:::.|:|..:.|...|::::.|:.:||:|::. :.|.|..||.|||:.|::|...:.
  Fly   527 MDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHFMMSH 591

  Fly   607 CAPGEYLIHKGDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQMTATTNS 671
            .|||:.|.|.|::::.:.::..||:|||:||.|||||||||:.|...              ..:|
  Fly   592 SAPGDLLYHTGESIDSLCFIVTGSLEVIQDDEVVAILGKGDVFGDQF--------------WKDS 642

  Fly   672 AGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDLTCNLREGY------ 730
            |    |.:|:::::|||||||..|....|:|||..|..:...||.::.  ||.|||...
  Fly   643 A----VGQSAANVRALTYCDLHAIKRDKLLEVLDFYSAFANSFARNLV--LTYNLRHRLIFRKVA 701

  Fly   731 -------------------ENQDSDIGPSFP----LPSISEDDENREEAEEGGKGEKENGGGP-- 770
                               :|||..:...|.    .|.:...  ::|.....|:.:.|.|.|.
  Fly   702 DVKREKELAERRKNEPQLPQNQDHLVRKIFSKFRRTPQVQAG--SKELVGGSGQSDVEKGDGEVE 764

  Fly   771 -----------------PSGASPLHNISNSPLHATRSPLLGMGSPRNQRLHQRGR-----SLITL 813
                             .:.|:|    |.||   :.||..|..|.|:.|..:.||     |:.:.
  Fly   765 RTKLPAKLTLTEDARILSTAAAP----SPSP---SPSPSSGPPSARSTRASKWGRLLGSSSVDSA 822

  Fly   814 RETNKR---HRTLNAACSLDRGSFEEPEPLEEEQSSGG-------KRPSLERLDSQVSTLHQDVA 868
            .:|:.:   .|:|:|..|| |.|..:........|:||       |.|.|:.  ||.:...||..
  Fly   823 SDTSAKVAVSRSLSARESL-RESTAQARQSSTSSSNGGQGNKVFPKAPKLQA--SQATLARQDTI 884

  Fly   869 QLSAEVRNAISALQEMTFTSNAMTSHSSL-KFPPARSIPNISGVAGTRSGVAVEHGLMGGVLAAA 932
            ....||.::..:.........|..|.::: ..||..:..:.:..||...|    .|..|.|:|..
  Fly   885 DEGGEVDSSPPSRDSRVVIEGAAVSSATVGPSPPVATTSSAAAGAGVSGG----PGSGGTVVAIV 945

  Fly   933 ELA----AMQRSSSHPPEVWGRDVQLPTSNTASSKAPSPVEPKKTMTSRSSQTDFY----RIDFP 989
            ..|    |::|.         |.:::                   .:||::.:|.|    |...|
  Fly   946 TKADRNLALERE---------RQIEM-------------------ASSRATTSDTYDTGLRETPP 982

  Fly   990 TFERFVLANPRLVLGLLGIEPAIKNEMDLLQQKQTLQISPLNTIDECVSPSDHNLA----SSKER 1050
            |     ||...|:..:|.::..::.|:..:||:       :..|::.:......||    |....
  Fly   983 T-----LAQRDLIATVLDMKVDVRLELQRMQQR-------IGRIEDLLGELVKRLAPGAGSGGNA 1035

  Fly  1051 LITSSAVPTPGRIYPPLDDENSNDFRWTMKHSASHHSC--CKSTDALLSPEEQPPISIL--PVDA 1111
            ...||...|||       ||                .|  |.:........:.||.|.:  |||.
  Fly  1036 PDNSSGQTTPG-------DE----------------ICAGCGAGGGGTPTTQAPPTSAVTSPVDT 1077

  Fly  1112 TPAPSVQEVRSSKRSLRKSTSGSNSSLSSSSSSSNSCLVSQSTGNLTTTNASVHCSNSSQSVASV 1176
            .              :..|:.|::.|.|.:.:.:.|.:.......|....|:|..|.....:..:
  Fly  1078 V--------------ITISSPGASGSGSGTGAGAGSAVAGAGGAGLLNPGATVVSSAGGNGLGPL 1128

  Fly  1177 ATTRRASWKLQHSRSGEYRRLSEATAEYSPPAKTPLPVAGVS 1218
            ...:|.|    .||...           :||.:|....||.:
  Fly  1129 MLKKRRS----KSRKAP-----------APPKQTLASTAGTA 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS_9	40..133	CDD:463873	40/111 (36%)
		PLN03192	270..>650	CDD:215625	176/399 (44%)
		cNMP	586..716	CDD:197516	49/129 (38%)
eag	NP_001036275.1	PAS_9	40..155	CDD:463873	42/117 (36%)
		Ion_trans	238..499	CDD:459842	127/264 (48%)
		CAP_ED	571..682	CDD:237999	48/128 (38%)