Protein Alignment Elk and CngA

DIOPT Version :10

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_061510131.1
• Gene: CngA / 1280008
• VectorBaseID: AGAMI1_009565
• Length: 853
• Species: Anopheles gambiae
• Alignment Length: 849
• Identity: 182/849 - (21%)
• Similarity: 334/849 - (39%)
• Gaps: 196/849 - (23%)

  Fly   165 SNAGMLGLGGL--PGLGG-----PAASDGDTEAGEGNNLDVPAGCNMGRRRSRAVLYQLSGHYKP 222
            :|......||.  |.|||     ||...|.|...             |||:..|.....:...:|
Mosquito    90 TNPSFSTTGGTPPPPLGGSGRVAPATGSGTTPTA-------------GRRQQAAAALPFTTRNRP 141

  Fly   223 EKGGVKTKLKLGNNFMHSTEAPFPEY--------------KTQSIKKS----------------- 256
            |   |.|:|.:.....|.::|.....              |..|:::|
Mosquito   142 E---VATELPVTPKNNHLSQAVIESERGDVQDQPSAGRRGKLSSLRRSLNALRCRISKRGRSKPP 203

  Fly   257 ----------------RL---------ILPHYGVFKGI-----------WDWVILVATFYVALMV 285
                            ||         .:|..||...:           |..|:.:|..|..:.|
Mosquito   204 DQFLDKFSAASATSDTRLHQAGCVAPQAVPSDGVCSRLSVDPSLPSHYRWLSVVSLAVLYNIIFV 268

  Fly   286 PYNAAFAKADRQTKV----SDVIVEALFIVDILLNFRTTFVSRKGEVVSNSKQIAINYL---RGW 343
            ...|.|.:.::|..|    .|.:.:.:::.|.|::....:: .:|.:|.::.::..:|.   |.|
Mosquito   269 IGRAVFWELNKQASVLWWILDYLCDFIYLTDTLVHCHEGYL-EQGLLVRDAPKLRKHYFSKQRWW 332

  Fly   344 FALDLLAALPFDHLYASDLYDGEDSHIH-------LVKLTRLLRLARLLQKIDRYSQHT----AM 397
              ||:::.||.|..|   ::....|...       :|::.|||||.|:.:..||....|    |.
Mosquito   333 --LDVVSMLPTDLAY---IWWAPSSCAATRLPCPIIVRINRLLRLPRMWEWFDRTETATGYPNAF 392

  Fly   398 ILTLLMFSFTLAAHWLACIWYVIAVKEYEWFPESNIGWLQLLAERKNASVAILTTAETYSTALYF 462
            .:..::.:..:..||.||:::.|:..    ...|...|:..:...||     ||.:..|..:.|:
Mosquito   393 RICKVVLAILVLIHWNACLYFAISYA----LGFSTDNWVYNINGPKN-----LTLSRQYIYSFYW 448

  Fly   463 TFTSLTSVGFGNVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKD 527
            :..:||::|......| .||.:|.:...|.|.|:.|.:.||:.::|..|...|..::::...:|.
Mosquito   449 STLTLTTIGETPTPEN-DAEYLFVVADFLAGVLIFATIVGNIGSMISNMNVTRVEFQNRMDGVKQ 512

  Fly   528 FVALHNMPKELKQRIEDYFQTSWSLSHGIDIYETLREFPEELRGDVSMHLHREIL-QLPIFEAAS 591
            ::|...:..||:.|:..:|..:|:.|..:|....|...|::|:.::::.:|.:.| |:.||:...
Mosquito   513 YMAFRKVGGELEARVIRWFAYTWAQSGALDEERVLAALPDKLKAEIAIRVHMDTLRQVRIFQDCE 577

  Fly   592 QGCLKLLSLHIKTNFCAPGEYLIHKGDALNYIYYLCNGSMEVIKDD--MVVAILGKGDLVGSDIN 654
            .|.|:.|.|.:|....:||:|:..|||....:|.:..||:.|:.||  .|:|.||.|.:.| :::
Mosquito   578 PGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGSLSVVADDGITVLATLGAGSVFG-EVS 641

  Fly   655 VHLVATSNGQMTATTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQ 719
            |..:|   |..|..          |.:::::::.|.||.|:....|.|.|..|||.:....
Mosquito   642 VLEIA---GNRTGN----------RRTANVRSIGYSDLFCLAKRDLWETLADYPEARASLT---- 689

  Fly   720 HDLTCNL--REGYENQDSDIGPSFPLPSISEDDENREEAEEGGKGEKENGGGPPSGASPLHNISN 782
             :..|.|  ::|..::           ::..:.:..:::.|.|....|            ..:.|
Mosquito   690 -ERGCQLLRKDGLLDE-----------AVFANAQQTQDSLESGVARLE------------QTVEN 730

  Fly   783 SPLHATRSPLLGMGSPRNQRLHQRGRSLITLRETNKRHRTLNAACSLDRGSFEEPEPLEEEQSSG 847
            ..|...|  ||...|....:|.||         .:|....:.......||:..:....:.:..:|
Mosquito   731 LNLRLAR--LLAEYSASQAKLKQR---------ISKLEDRVQKPSPTSRGAEAKAAHQQLQHPAG 784

  Fly   848 GKRPSLERLDSQVSTLHQDVAQLSAEVRNAISALQEMTFTSNAMTSHSSLKFPPARSIPNISGVA 912
            |            |.......:|..:.|.:.|:....|.|:.|..|.:::  ..:.:.|.:.|.|
Mosquito   785 G------------SAASNAAGRLRTQRRKSHSSTTTTTTTTAAEESLTTV--TASGTTPTVPGAA 835

  Fly   913 GTRS 916
            |:.|
Mosquito   836 GSAS 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS_9	40..133	CDD:463873
		PLN03192	270..>650	CDD:215625	103/400 (26%)
		cNMP	586..716	CDD:197516	40/131 (31%)
CngA	XP_061510131.1	None