Protein Alignment Elk and CNGA4

DIOPT Version :9

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_016872706.1
• Gene: CNGA4 / 1262
• HGNCID: 2152
• Length: 577
• Species: Homo sapiens
• Alignment Length: 632
• Identity: 156/632 - (24%)
• Similarity: 276/632 - (43%)
• Gaps: 151/632 - (23%)

  Fly   229 TKLKLGNNFMHSTEA--PFPEYKTQSIKKSRLILP--------HYG-----VFKGIWDWVILVA- 277
            ||:|       :||:  |.|       .|:|.:||        :|.     ||..:::.:|||.
Human     5 TKVK-------TTESSPPAP-------SKARKLLPVLDPSGDYYYWWLNTMVFPVMYNLIILVCR 55

  Fly   278 TFYVALMVPYNAAFAKADRQTKVSDVIVEALFIVDILLNFRTTFVSRKGEVVSNSKQIAINYLRG 342
            ..:..|...|..|:.       |.|...:.|:::|:::.|.|.|: .:|.:|.:..:|:..|:|.
Human    56 ACFPDLQHGYLVAWL-------VLDYTSDLLYLLDMVVRFHTGFL-EQGILVVDKGRISSRYVRT 112

  Fly   343 W-FALDLLAALPFDHLYASDLYDGEDSHIHLVKLTRLLRLARLLQKIDRYSQHTA-----MILTL 401
            | |.|||.:.:|.|.:|..     ...|...::|.|.||..||.:..||....||     .|..|
Human   113 WSFFLDLASLMPTDVVYVR-----LGPHTPTLRLNRFLRAPRLFEAFDRTETRTAYPNAFRIAKL 172

  Fly   402 LMFSFTLAAHWLACIWYVIAVKEY------EW-FPE-SNIGWLQLLAERKNASVAILTTAETYST 458
            :::.| :..||.:|:::  |:..|      .| :|: :..|:.:|..:              |..
Human   173 MLYIF-VVIHWNSCLYF--ALSRYLGFGRDAWVYPDPAQPGFERLRRQ--------------YLY 220

  Fly   459 ALYFTFTSLTSVGFGNVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWR 523
            :.||:...||:||.....|. ..|.:|.:...|:..:..|.:.|:::::|..|.:..:.:.....
Human   221 SFYFSTLILTTVGDTPPPAR-EEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYPDHA 284

  Fly   524 DLKDFVALHNMPKELKQRIEDYF---QTSWSLSHGIDIYETLREFPEELRGDVSMHLHREIL-QL 584
            .:|.::.|.::.::|::|:.|::   |.:..:::.:.|   |:..||.||.:|::.:|...| ::
Human   285 LVKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEVAI---LQHLPERLRAEVAVSVHLSTLSRV 346

  Fly   585 PIFEAASQGCLKLLSLHIKTNFCAPGEYLIHKGDALNYIYYLCNGSMEVIKDDMVV--AILGKGD 647
            .||:......|:.|.|.::....:||||:..|||....:|.:..|.:.|:.||.:.  |:||.|.
Human   347 QIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREGQLAVVADDGITQYAVLGAGL 411

  Fly   648 LVG--SDINVHLVATSNGQMTATTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEY 710
            ..|  |.||:          .||.|.:|.    |.:::||:|.|.||.|:....|.|||..||:.
Human   412 YFGEISIINI----------KATGNMSGN----RRTANIKSLGYSDLFCLSKEDLREVLSEYPQA 462

  Fly   711 Q---QQFANDI---QHDLTCN-------LRE-------GYENQDSDIGPSF-------------- 741
            |   ::...:|   .:.|..|       |:|       |.:.|..|:...|
Human   463 QTIMEEKGREILLKMNKLDVNAEAAEIALQEATESRLRGLDQQLDDLQTKFARLLAELESSALKI 527

  Fly   742 --------------PLPSISEDDENREEAEEGGKGEKENGG---GPP 771
                          |:|....:.::..|.|||...::|...   |||
Human   528 AYRIERLEWQTREWPMPEDLAEADDEGEPEEGTSKDEEGRASQEGPP 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075
		PAS_3	41..129	CDD:285623
		Ion_trans	285..516	CDD:278921	60/244 (25%)
		Ion_trans_2	<455..510	CDD:285168	14/54 (26%)
		Crp	583..>650	CDD:223736	21/68 (31%)
		CAP_ED	586..715	CDD:237999	44/135 (33%)
CNGA4	XP_016872706.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144997
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840