DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elk and LOC101883600

DIOPT Version :9

Sequence 1:	NP_477009.1	Gene:	Elk / 37047	FlyBaseID:	FBgn0011589	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	XP_005172600.2	Gene:	LOC101883600 / 101883600	-ID:	-	Length:	654	Species:	Danio rerio

Alignment Length:	718	Identity:	231/718 - (32%)
Similarity:	346/718 - (48%)	Gaps:	156/718 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 DGEDSHIHLVKLTRLLRLARLLQKIDRYSQHTAMILTLLMFSFTLAAHWLACIWYVIAVKEYEWF 428
            |...:.|.|:|..|||||.|:.:|:||||::.|.:|.|||..|.|.|||||||||.|...|..:.
Zfish    30 DDTTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVEKSYL 94

  Fly   429 PESNIGWLQLL----AERKNAS--VAILTTAETYSTALYFTFTSLTSVGFGNVSANTTAEKVFTI 487
             |..||||..|    .:|.|.|  .:..:..:.|.|||||||:|||||||||||.||.:||:|:|
Zfish    95 -EHKIGWLDNLEVSIGKRSNTSDPGSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSI 158

  Fly   488 IMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDYFQTSWSL 552
            .:||||:||:|.:||||:|||||:||..:.|..:...:|:|:..|.:|..|:||:|:|||.||:.
Zfish   159 CVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHSWTY 223

  Fly   553 SHGIDIYETLREFPEELRGDVSMHLHREILQ-LPIFEAASQGCLKLLSLHIKTNFCAPGEYLIHK 616
            ::|||:...|:.|||.|:.|:.:||:..:|| ...|..|:||||:.|::..|.....||:.|:|.
Zfish   224 TNGIDMNMVLKGFPECLQADICLHLNDSLLQGCKAFRGATQGCLRALAIRFKNTHAPPGDTLVHC 288

  Fly   617 GDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQMTATTNSAGQDVVVRSS 681
            ||.|..:|:|..||:|::|||:|||||||.|:.|.  .:||.|...                :|:
Zfish   289 GDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGE--MIHLYAKPG----------------KSN 335

  Fly   682 SDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDLTCNLREGYENQDSDIGPSFPLPSI 746
            :|::||:||||..|....|:|||.:|||:...|..::  :||.|||      |.:...::...|.
Zfish   336 ADVRALSYCDLHTIQREELLEVLDMYPEFADYFLTNL--ELTFNLR------DDNTKATYSQSSD 392

  Fly   747 SEDDENREEAEEGGKGEKENGGGPPSGASPLHNISNSPLHATRSPLLGMGSPRNQRLHQRGRSLI 811
            |:.:||:...:...|.:...||          ::..:...:.|       ..|..||..:..|..
Zfish   393 SDGEENKSRRKISVKRKSSQGG----------SLREADSESRR-------ERRESRLSSKRSSEE 440

  Fly   812 TLRETNKRHRTLNAA----------CS-----LDRGSFE----------------------EPEP 839
            .....:::.|.|.||          ||     .|:.:::                      |.|.
Zfish   441 RSASRDEQQRILGAAIMEDPPVQSCCSPACEDKDKRTYDDLQAGRWLSESVKADTQERCCAEEED 505

  Fly   840 LEEEQSSGGKRPSLERLDSQVSTLHQDVAQLSAEVRNAISALQEMTFTSNAMTSHSSL----KFP 900
            |:.|.:.|.....|::|...:|.|..   |:::::::.::.||..|..  ...::|||    |.|
Zfish   506 LDCEITYGEVENRLDQLQEHLSRLEY---QMTSDIQSILTLLQRQTCL--GPPAYSSLTAEYKRP 565

  Fly   901 PARSIPNISGVAGTRSGVAVEHGLMGGVLAAAELAAMQRSSSHPPEVWGRDVQLPTSNTASSKAP 965
            ..|..|:.|........              ||..||.|  .||            ::|.||..|
Zfish   566 AIRIQPSASETHTPPQN--------------AEFLAMTR--IHP------------NSTDSSSGP 602

  Fly   966 SPVEPKKTMTSRSSQTDFYRIDFPTFERFVLANPRLVLGLLGIEPAIKNEMDLLQQKQT----LQ 1026
            :                           .:.:||..:.|.......:.|...|...:||    |:
Zfish   603 N---------------------------LINSNPNQIHGTPSSTQDLTNRQTLPLGRQTSKPLLR 640

  Fly  1027 ISP 1029
            :||
Zfish   641 LSP 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075
		PAS_3	41..129	CDD:285623
		Ion_trans	285..516	CDD:278921	85/157 (54%)
		Ion_trans_2	<455..510	CDD:285168	39/54 (72%)
		Crp	583..>650	CDD:223736	32/67 (48%)
		CAP_ED	586..715	CDD:237999	51/128 (40%)
LOC101883600	XP_005172600.2	Ion_trans	<22..184	CDD:306908	83/154 (54%)
LOC101883600	XP_005172600.2	CAP_ED	258..369	CDD:237999	51/128 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247304at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010