Protein Alignment Elk and hcn4

DIOPT Version :9

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_002944030.2
• Gene: hcn4 / 100498501
• XenbaseID: XB-GENE-940130
• Length: 2061
• Species: Xenopus tropicalis
• Alignment Length: 985
• Identity: 207/985 - (21%)
• Similarity: 385/985 - (39%)
• Gaps: 249/985 - (25%)

  Fly   245 FPEYKTQSIKKSRL------ILPHYGVFKGIWDWVILVATFYVALMVPYNAAFAKADRQTK---V 300
            |..:|...|::.|:      |:..|..|:..||.::|:......:::|....|.| |..|.   |
 Frog  1213 FGSHKAVEIEQQRVKSAGSWIIHPYSDFRFYWDLIMLLLMVANLIILPVGITFFK-DENTPPWIV 1276

  Fly   301 SDVIVEALFIVDILLNFRTTFVSRKG-EVVSNSKQIAINYLRGWFALDLLAALPFDHLY-ASDLY 363
            .:|:.:..|:.|::|||||..|.... |::.:...|.:.||:.||.:|.::::|.|::: ..||.
 Frog  1277 FNVLSDTFFLADLVLNFRTGIVVEDNTEIILDPHTIKMKYLKSWFLVDFVSSIPVDYIFLIVDLE 1341

  Fly   364 DGEDSHIH-------------LVKLTRLLRLARLLQKIDRYSQHTAMILTL---------LMFSF 406
            ...|:.::             ::.|.|||||:||::.|.::.:...|...|         |:...
 Frog  1342 TNVDTEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMM 1406

  Fly   407 TLAAHWLACIWYVIAVKEYEWFPESNIGWLQLLAERKNASVAILTTAETYSTALYFTFTSLTSVG 471
            .|..||..|:.:::.:  .:.|||.  .|:.:      ..:|..:..:.||.|::...:.:..:|
 Frog  1407 LLLCHWDGCLQFLVPM--LQDFPED--CWVSI------NHMANESWGKQYSHAIFKAMSHMLCIG 1461

  Fly   472 FGNVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPK 536
            :|..:.....:...|::.|::||..:|:..|:.||:||.:.|.|..|:.|::.::.:::.|.:|.
 Frog  1462 YGQQAPEGMTDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPP 1526

  Fly   537 ELKQRIEDYFQTSWSLSHGIDIYETLREFPEELRGD-VSMHLHREILQLPIFEAASQGCLKLLSL 600
            :.:|||.:|::..:. ....|....|.|..|.|:.: |:.:....:..:|:|..|....:..:..
 Frog  1527 DTRQRIHEYYEHRYQ-GKMFDEENILGELSEPLKEEIVNFNCRNLVANMPLFANADPNFVTAMLT 1590

  Fly   601 HIKTNFCAPGEYLIHKGDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQM 665
            .::.....||:|:|.:|.....:|::.:|.:.::........|..|...|     .:...:.|:.
 Frog  1591 KLRFEVFQPGDYIIREGTVGKKMYFIQHGVVSILTRGSKETKLSDGSYFG-----EICLLTRGRR 1650

  Fly   666 TATTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDL-------T 723
            ||:               ::|.|||.|..:.:....|||..||..::.|.......|       :
 Frog  1651 TAS---------------VRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAMDRLDRIGKKNS 1700

  Fly   724 CNLREGYENQDSDIGPSFPLPSISEDDENREEAEEGGKGEKENGGGPPSGASPLHNISN-SPLHA 787
            ..||:..||....:              |.|..::..|.:::..          |||.: ..|.|
 Frog  1701 ILLRKRAENSSGSV--------------NNEIIQQIVKHDRDTA----------HNIQDIQCLAA 1741

  Fly   788 TRSPLLGMGSPRNQRLHQRGRSLITLRETNKR-------HRTLNAACSLDRGSFEEPEPLEEEQS 845
            ||.|                         ||.       |..|..|.:
 Frog  1742 TRDP-------------------------NKPFIWEPLVHAPLQTAAA----------------- 1764

  Fly   846 SGGKRPSLERLDSQVSTLHQDVAQLSAEVRNAISALQEMTFTS-NAMTSHSSLKFPPARSIP-NI 908
                     ..:..::..||.  .|.|.|.....:|.|..:.| .|..|..||:    .|.| ::
 Frog  1765 ---------TTNVAIALTHQQ--NLQANVFLPPLSLPETAYVSRQARRSQPSLR----GSHPSSV 1814

  Fly   909 SGVAGTRSGVAVEHGLMGGVLAAAELAAMQRSSSHPPEVWGRDVQLPTSNTASSK------APSP 967
            |..:||:|.:....|     ::.:..:.:|:.|     :.|:..|:|...:.|.:      |..|
 Frog  1815 SSPSGTQSHLQTPLG-----ISPSSPSGVQKQS-----INGQCPQIPIRLSQSQRGEPQTAAKPP 1869

  Fly   968 VEPKKTMTSRSSQTDFYRIDFPTFERFVL------ANPRLVLGLL-------GIEPAIKNEMDLL 1019
            :.|.:...|||..|        :....||      |...:|.|.|       .:..|..:.:.||
 Frog  1870 ILPSQVQLSRSRGT--------SASTSVLQQGMGPAGSPVVPGSLSGRTLHYSLSRASGSHISLL 1926

  Fly  1020 QQK-----------QTLQISPLNTIDECVSPSDHNLASSKERLITSSAVPTPGRIYPPLDDENSN 1073
            .|:           :::|..|:..:.:.|            ||:::|....|.::....|.
 Frog  1927 MQQAASSPQQLVKYRSIQGLPIGRLSQDV------------RLMSASQPSLPNKVTHQQDG---- 1975

  Fly  1074 DFRWTMKHSASHHSCCKSTDALL----------SPEEQP--PI--SILPVDATPAPSVQEVRSSK 1124
                :|...||:.| ..:..|:|          .|::||  |:  |..||..:..|  |...|:.
 Frog  1976 ----SMLQIASNKS-SPTVSAMLVRPSLPSPSAHPQQQPSGPLVFSGRPVSGSATP--QSPVSAP 2033

  Fly  1125 RSLRKSTSGS 1134
            |...:|..||
 Frog  2034 RPAGQSRKGS 2043

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075
		PAS_3	41..129	CDD:285623
		Ion_trans	285..516	CDD:278921	64/257 (25%)
		Ion_trans_2	<455..510	CDD:285168	14/54 (26%)
		Crp	583..>650	CDD:223736	12/66 (18%)
		CAP_ED	586..715	CDD:237999	25/128 (20%)
hcn4	XP_002944030.2	Plasmodium_HRP	<67..248	CDD:253181
		Ion_trans_N	1197..1239	CDD:285597	6/25 (24%)
		Ion_trans	1259..1506	CDD:278921	64/257 (25%)
		Crp	1570..>1708	CDD:223736	30/157 (19%)
		CAP_ED	1576..1684	CDD:237999	25/127 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910