DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Elk and cnga3

DIOPT Version :9

Sequence 1:	NP_477009.1	Gene:	Elk / 37047	FlyBaseID:	FBgn0011589	Length:	1284	Species:	Drosophila melanogaster
Sequence 2:	XP_031752880.1	Gene:	cnga3 / 100494840	XenbaseID:	XB-GENE-948568	Length:	737	Species:	Xenopus tropicalis

Alignment Length:	474	Identity:	119/474 - (25%)
Similarity:	212/474 - (44%)	Gaps:	85/474 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 WDWVILVATFYVALMVPYNAAFAKADRQT----KVSDVIVEALFIVDILLNFRTTFVSRKGEVVS 330
            |..:|.|...|....:...|.|.:..|.:    .|.|...:.::|.|.|:.|||.|: .:|.:|.
Frog   213 WLSIISVPVLYNWCFLVCRACFDELQRNSIILWLVLDYTADVIYITDTLVRFRTGFL-EQGLLVK 276

  Fly   331 NSKQIAINYLR-GWFALDLLAALPFDHLYASDLYDGEDSHIHL----VKLTRLLRLARLLQKIDR 390
            ::|::..||.: ..|.||||:.||.|..|..         |.|    ::..||||..|:.:..||
Frog   277 DAKKLKENYSKTRQFKLDLLSLLPTDLTYLK---------IGLNYPELRFNRLLRFGRMFEFFDR 332

  Fly   391 YSQHT---------AMILTLLMFSFTLAAHWLACIWYVIA--------VKEYEWFPESNIGWLQL 438
            ....|         .::|.:|     :..||.|||::.|:        ...|........|.|
Frog   333 TETRTNYPNIFRIGNLVLYIL-----IIIHWNACIYFAISKAIGFGTDTWVYPNISHPEYGRL-- 390

  Fly   439 LAERKNASVAILTTAETYSTALYFTFTSLTSVGFGNVSANT-----TAEKVFTIIMMLIGALMHA 498
                          |..|..:||::..:||::|      .|     ..|.:|.:...|||.|:.|
Frog   391 --------------ARKYIYSLYWSTLTLTTIG------ETPPPVKDIEFLFVVFDFLIGVLIFA 435

  Fly   499 VVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDYFQTSWSLSHGIDIYETLR 563
            .:.|||.::|..|.:.::.::||...:|.::....:.|:|:.|:..:|...|:....:|..|.|:
Frog   436 TIVGNVGSMISNMNASKAEFQSKIDSIKQYMQFRKVTKDLEARVIKWFDYLWTNKKTMDEKEVLK 500

  Fly   564 EFPEELRGDVSMHLHREIL-QLPIFEAASQGCLKLLSLHIKTNFCAPGEYLIHKGDALNYIYYLC 627
            ..|::|:.::::::|.:.| ::.||:....|.|..|.|.::....:||:|:..|||....:|.:.
Frog   501 SLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGREMYIIK 565

  Fly   628 NGSMEVIKDDMVV--AILGKGDLVGSDINVHLVATSNGQMTATTNSAGQDVVVRSSSDIKALTYC 690
            .|.:.|:.||.|.  .:|..|...|....:::..:.:|.              |.:::|:::.|.
Frog   566 EGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGN--------------RRTANIRSIGYS 616

  Fly   691 DLKCIHMGGLVEVLRLYPE 709
            ||.|:....|:|.|..||:
Frog   617 DLFCLSKDDLMEALTEYPD 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075
		PAS_3	41..129	CDD:285623
		Ion_trans	285..516	CDD:278921	67/261 (26%)
		Ion_trans_2	<455..510	CDD:285168	18/59 (31%)
		Crp	583..>650	CDD:223736	20/68 (29%)
		CAP_ED	586..715	CDD:237999	33/126 (26%)
cnga3	XP_031752880.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910