Protein Alignment Elk and kcnh6

DIOPT Version :9

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_031759588.1
• Gene: kcnh6 / 100491983
• XenbaseID: XB-GENE-990943
• Length: 1194
• Species: Xenopus tropicalis
• Alignment Length: 1235
• Identity: 369/1235 - (29%)
• Similarity: 578/1235 - (46%)
• Gaps: 321/1235 - (25%)

  Fly     1 MPARKGLLAPQNTFLDTIATRFDGTHSNFVLGNAQANGNPIVYCSDGFVDLTGYSRAQIMQKGCS 65
            ||.|:|.:||||||||||..:|:|....|::.||:.....::||:|.|..:.||:||::||:.|:
 Frog     1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDAFCAMCGYTRAEVMQRPCT 65

  Fly    66 CHFLYGPDTKEEHKQQIEKSLSNKMELKLEVIFYKKE-----GAPFWCLFDIVPIKNEKRDVVLF 125
            |.|||||.|......||.::|....|.|:|:.||:|:     |:.|.||.|:||:|||...|::|
 Frog    66 CDFLYGPRTTASSASQIAQALVGSEERKVEIAFYRKDVFGSVGSCFLCLVDVVPVKNEDGSVIMF 130

  Fly   126 LASHKDITHTKMLEMNVNEECD---------------------SVFALTAA----------LLGA 159
            :.:. ::...|.|.::.|::.:                     ::.|||.:          ::..
 Frog   131 ILNF-EVVMEKDLLVSPNKDSNHKVQSHWFPSGRGKSFKLKLPALLALTGSKQSLPQEDPDVVVV 194

  Fly   160 RFRAGSNAGM----LGLGGLPGLGGPAASDGDTEAG----------EGN---------------- 194
            .|...|:..:    :.|..:....|..:.|.....|          |||
 Frog   195 DFSKHSSDTVALEEMNLTPINNCIGSQSEDQQALIGSKEPKAPPDEEGNKESAVQSSPHTDKDLL 259

  Fly   195 NLDVP-AGCNMGRRRSRAVLYQL-SGHYKPEKGGVKTKLK-----------LGN---NFMHSTE- 242
            |||:. :.|::.|.|||...|.: ......|...:|..|:           :.|   |.::||.
 Frog   260 NLDMSFSNCSLSRSRSRESFYSIRRASSVDEIEAMKVDLEKFRNRNSSTGAMNNIRANLLNSTSD 324

  Fly   243 --------------------------------------AP------------------------F 245
                                                  ||                        .
 Frog   325 SDLMRYRTISKIPQITLNFVDFKGDSFLTSPSNEKEIIAPSKLKDRTHNVTEKVTQVLSLGADVL 389

  Fly   246 PEYKTQSIKKSRLILPHYGVFKGIWDWVILVATFYVALMVPYNAAFAKADRQ------------- 297
            ||||.|:.:..:..:.||..||.:|||:||:...|.|:..||:|||...|::
 Frog   390 PEYKLQAPRIHKWTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLGDQEEAENEQCGYSCNP 454

  Fly   298 TKVSDVIVEALFIVDILLNFRTTFVSRKGEVVSNSKQIAINYLRGWFALDLLAALPFDHLY---A 359
            ..|.|:||:.:||:|||:|||||:|:...||||:..:|||:|.:|||.:|::||:|||.|.   .
 Frog   455 LSVVDLIVDIMFIIDILINFRTTYVNTNEEVVSHPGKIAIHYFKGWFLIDMVAAIPFDLLIFGSG 519

  Fly   360 SDLYDGED--------SHIHLVKLTRLLRLARLLQKIDRYSQHTAMILTLLMFSFTLAAHWLACI 416
            |:.....|        :.|.|:|..|||||.|:.:|:||||::.|.:|.|||.:|.|.|||||||
 Frog   520 SEEIKRPDEGANKETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACI 584

  Fly   417 WYVIAVKEY---EWFPESNIGWLQLLAERKNASVAIL-----TTAET-------YSTALYFTFTS 466
            ||.|...|:   |:.|   ||||..|      .:.|:     |.|::       |.|||||||:|
 Frog   585 WYAIGNMEHYDQEYRP---IGWLYSL------GIQIMKPYNSTNAKSGPSINDKYVTALYFTFSS 640

  Fly   467 LTSVGFGNVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVAL 531
            ||||||||||.||.:||:|:|.:||||:||:|.:||||:|||||:||..:.|.::...:::|:..
 Frog   641 LTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRF 705

  Fly   532 HNMPKELKQRIEDYFQTSWSLSHGIDIYETLREFPEELRGDVSMHLHREILQ-LPIFEAASQGCL 595
            |.:|..|:||:|:|||.:||.::|||:...|:.|||.|:.|:.:||:|.:|| ...|:.|::|||
 Frog   706 HQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQNCKPFKGATKGCL 770

  Fly   596 KLLSLHIKTNFCAPGEYLIHKGDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVAT 660
            :.|::..||....||:.|:|.||.|..:|:|..||:|:::.|:|||||||.|:.|..||::.
 Frog   771 RALAMKFKTTHAPPGDTLVHAGDVLTAVYFLSRGSIEILRGDVVVAILGKNDIFGEPINLYA--- 832

  Fly   661 SNGQMTATTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDLTCN 725
                      ..|     :|::|::|||||||..||...|:|||.:|||:...|.:.:  ::|.|
 Frog   833 ----------RPG-----KSNADVRALTYCDLHKIHREDLLEVLDMYPEFSDYFWSSL--EITFN 880

  Fly   726 LREGYENQDSDIGPSFPLPSISEDDENR-------------EEAEEGGKGEKENGGGPPSGASPL 777
            ||      |:::.|..|....|:...||             ::||..|:.::....|..|..:|
 Frog   881 LR------DTNMIPGSPSSDDSDSGFNRLRRRKLSFRRRTDKDAENAGEAKRSQRMGRLSRNTP- 938

  Fly   778 HNISNSPLHATRSPLLGMGSPRNQRLHQRGRSLITLRETNKRHRTLNAACSLDRGSFEEPE---- 838
             ...:..|...:....|..|..:........|..|:..:..|....|::.|:.|||..|.:
 Frog   939 -TCESKGLDWDKQLSTGPSSSSSSDDENPPPSSNTVELSPTRAMFTNSSFSVPRGSEAEGDNGTA 1002

  Fly   839 ----------------------------------PLEEEQSSGGKRPSLER-----LDSQVSTLH 864
                                              .:....:.||..||:.|     :.:::..|.
 Frog  1003 DVCNHLSGAFSGVSNIFSFWGDRAGGQYQELPRCTIPAHTALGGTAPSMSRRQKCEIGNRLDVLQ 1067

  Fly   865 QDVAQLSAEVRNAISALQEMTFTSNAMT--SHSSLKFPPARSI------------PNISGVAGTR 915
            :.:.:|.:.:...|:.:.::.....|:.  ::|::..||  .|            ||::|::.|.
 Frog  1068 KQLNRLESRMVTDINTIMQLLQKQAALVPPAYSTVSSPP--QIPGYPPGGDHIVQPNLAGLSQTL 1130

  Fly   916 SGVAVEHGLMGGVLAAAELAAMQRSSSHPPEVWGRDVQLPTSNTASSKAPSPV--EPKKTMTSRS 978
            :.::       .|....||...:......|.|                 |.||  ||:.:...||
 Frog  1131 ASIS-------QVYEYQELEGQRLDLCEMPLV-----------------PQPVNTEPRDSPRRRS 1171

  Fly   979  978
             Frog  1172  1171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075	39/100 (39%)
		PAS_3	41..129	CDD:285623	39/92 (42%)
		Ion_trans	285..516	CDD:278921	126/269 (47%)
		Ion_trans_2	<455..510	CDD:285168	39/61 (64%)
		Crp	583..>650	CDD:223736	30/67 (45%)
		CAP_ED	586..715	CDD:237999	51/128 (40%)
kcnh6	XP_031759588.1	PAS_9	29..135	CDD:404329	42/106 (40%)
		PLN03192	401..>866	CDD:215625	213/491 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247304at2759
OrthoFinder	1	1.000	-	-		FOG0000148
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010