Protein Alignment Elk and hcn1

DIOPT Version :10

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_031750156.1
• Gene: hcn1 / 100490760
• XenbaseID: XB-GENE-950265
• Length: 839
• Species: Xenopus tropicalis
• Alignment Length: 825
• Identity: 184/825 - (22%)
• Similarity: 338/825 - (40%)
• Gaps: 178/825 - (21%)

  Fly   247 EYKTQSIKKSRLILPH-YGVFKGIWDWVILVATFYVALMVPYNAAFAKADRQTK--VSDVIVEAL 308
            |.:.:.:|.:.:.:.| |..|:..||.::|:......:::|....|......|.  :.:|..:.:
 Frog    96 EKEQERVKTAGVWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTV 160

  Fly   309 FIVDILLNFRTTFV-SRKGEVVSNSKQIAINYLRGWFALDLLAALPFDHLYASDLYDGEDSHIH- 371
            |:.|:.:||||..| ....|::.:.|.|.:|||:.||.:|.::::|.|:::.. :..|.||.::
 Frog   161 FLFDLFMNFRTGIVIEDNSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLI-VEKGMDSEVYK 224

  Fly   372 ------------LVKLTRLLRLARLLQKIDRYSQHTAMILTL---------LMFSFTLAAHWLAC 415
                        ::.|.|||||:||::.|.::.:...|...|         |:....|..||..|
 Frog   225 TARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGC 289

  Fly   416 IWYVIAVKEYEWFPESNIGWLQLLAERKNASVAILTTAETYSTALYFTFTSLTSVGFGNVSANTT 480
            :.:::.:.: |:.|:.   |:.|      .::...:..:.||.||:...:.:..:|:|..:..:.
 Frog   290 LQFLVPLLQ-EFPPDC---WVSL------NNMVNDSWGKQYSYALFKAMSHMLCIGYGARAPVSM 344

  Fly   481 AEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDY 545
            ::...|::.|::||..:|:..|:.||:||.:.|.|..|:.|::.::.:::.|.:|.:::|:|.||
 Frog   345 SDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPSDMRQKIHDY 409

  Fly   546 FQTSWSLSHGIDIYETLREFPEELRGD-VSMHLHREILQLPIFEAASQGCLKLLSLHIKTNFCAP 609
            ::..:. ....|....|.|..:.||.: |:.:..:.:..:|:|..|....:..:...:|.....|
 Frog   410 YEHRYQ-GKIFDEDNILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLKFEVFQP 473

  Fly   610 GEYLIHKGDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQMTATTNSAGQ 674
            |:|:|.:|.....:|::.:|...||........|..|...|     .:...:.|:.||:
 Frog   474 GDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFG-----EICLLTKGRRTAS------ 527

  Fly   675 DVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQF-------------ANDI-----QHD 721
                     ::|.|||.|..:.:....|||..||..::.|             .|.|     |.|
 Frog   528 ---------VRAETYCRLYSLSVENFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILQQRFQKD 583

  Fly   722 LTCNLREGYENQDSDIGPSFPLPSISEDDENREEAEEGGKGEKENGGGPPSGASPLHNISNSPLH 786
            |...:   :.||:|:|     |..:...|  ||..|           |.||       :|...|.
 Frog   584 LNTGI---FNNQESEI-----LKQMLTQD--REMVE-----------GHPS-------VSYQQLP 620

  Fly   787 ATRSPLLGMGSPRNQRLHQRGRSLITLRETNKRHRTLNAACSLDRGSFEEPEPLEEEQ------- 844
            |       :.|..:..|..|.||           ..:..|.||..|:.:.|.|..:..
 Frog   621 A-------LNSSTSSSLRMRTRS-----------PPVYNANSLSHGNLQSPTPSPQTPQQAVVFS 667

  Fly   845 ----SSGGKRPSLERLDSQVSTLHQDVAQLSAEVRNAISALQEMTFTSNAMTSHSSLKFPPA--- 902
                :|....||::      |.|.....|.|:...:.:|.:|:....|.|...|...|...|
 Frog   668 PSSFTSAACSPSVQ------SPLAGRTFQYSSLTASQLSLIQQQQQASGASQIHEVHKSAQALAN 726

  Fly   903 --------------RSIPNISGVAGTRSGVAVEHGLMGGVLA----------AAELAAMQRSSSH 943
                          .|:|:.....|::     .|..:|..||          ||...:..||:..
 Frog   727 TNLTREVRPLSASQPSLPHEISTLGSK-----PHPTVGESLASLPQPISNVQAAGTQSGSRSNIP 786

  Fly   944 PPEVWGRDVQ---LPTSNTASSKAPSPVEPKK---TMTSRSSQTD 982
            |.....|.:.   ||.:...::..|||..|.|   |::|..:.||
 Frog   787 PRVALFRQMSSGALPPARVGATTQPSPAPPTKDSSTVSSTDTDTD 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS_9	40..133	CDD:463873
		PLN03192	270..>650	CDD:215625	95/405 (23%)
		cNMP	586..716	CDD:197516	29/142 (20%)
hcn1	XP_031750156.1	Ion_trans_N	73..115	CDD:400630	4/18 (22%)
		PLN03192	108..>587	CDD:215625	118/510 (23%)
		CAP_ED	450..558	CDD:237999	28/127 (22%)
		Atrophin-1	604..>816	CDD:460830	53/260 (20%)