Protein Alignment Elk and kcnh7

DIOPT Version :9

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_031749023.1
• Gene: kcnh7 / 100486080
• XenbaseID: XB-GENE-853944
• Length: 1205
• Species: Xenopus tropicalis
• Alignment Length: 1237
• Identity: 370/1237 - (29%)
• Similarity: 562/1237 - (45%)
• Gaps: 326/1237 - (26%)

  Fly     1 MPARKGLLAPQNTFLDTIATRFDGTHSNFVLGNAQANGNPIVYCSDGFVDLTGYSRAQIMQKGCS 65
            ||.|:|.:|||||||.||..:|:|.:..|::.||:.....|:||:|||.::||:||..:|||.|:
 Frog     1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCT 65

  Fly    66 CHFLYGPDTKEEHKQQIEKSLSNKMELKLEVIFYKKEGAPFWCLFDIVPIKNEKRDVVLFLASHK 130
            |.||:||:||.....||.::|....|.|:.|.:|.|:|:.|.|...|:|:||::...::|:.:.:
 Frog    66 CDFLHGPETKRHDIAQIAQALLGSEERKVVVTYYHKDGSTFLCSTHIIPVKNQEGVAMMFIMNFE 130

  Fly   131 DIT------------------------------------HTKM---------LEMNVNEECDSVF 150
            .:|                                    |.|.         :.::.::..|...
 Frog   131 YVTKIESPVSPERIPRLLPITPENRKLFGIQFPQLRLLSHRKQSLPQEDPDAVIVDSSKHSDDSM 195

  Fly   151 AL------------------TAALLGA----------------------------RFRAGSN--- 166
            |:                  |.||:.:                            |..|||:
 Frog   196 AMKHFKSPTKESCSPSEADDTKALIDSHKCSTLVNVTGPLDHSSPKRQWDQLFPDRLHAGSHISH 260

  Fly   167 -------AGMLGLGGLPGLGG----PAASDGDTEAGEGNNLDV---------------------- 198
                   ..|.....:..:.|    |.:...|..|.|.|..|.
 Frog   261 ARSKDSVCSMRRASSVHDIEGFSIHPKSVFRDRHASEDNGRDFKVSHSWMTGGPFNHIKSSLLGS 325

  Fly   199 PAGCNMGRRRSRAVLYQLSGHYKPEKGGVKTK----------------------------LKLGN 235
            .:..|:.:..:...:.||:.::...|...|..                            |.||.
 Frog   326 TSDSNLNKYSTINKIPQLTLNFSDVKNEKKASSPPSSEKTIIAPKVKERTHNVTEKVTQVLSLGA 390

  Fly   236 NFMHSTEAPFPEYKTQSIKKSRLILPHYGVFKGIWDWVILVATFYVALMVPYNAAFAKADRQTK- 299
            :.:       ||||.|:.:.::..:.||..||.:|||:||:...|.|:..||:|||...||:.:
 Frog   391 DVL-------PEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQK 448

  Fly   300 ------------VSDVIVEALFIVDILLNFRTTFVSRKGEVVSNSKQIAINYLRGWFALDLLAAL 352
                        |.|::|:.:||:|||:|||||:|::..||||:..:|||:|.:|||.:|::||:
 Frog   449 RRECGYSCNPLNVVDLMVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAI 513

  Fly   353 PFDHLYASDLYDGEDSHIHLVKLTRLLRLARLLQKIDRYSQHTAMILTLLMFSFTLAAHWLACIW 417
            |||.|......|...:.|.|:|..|||||.|:.:|:||||::.|.:|.|||..|.|.||||||||
 Frog   514 PFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIW 578

  Fly   418 YVIAVKEYEWFPESNIGWLQLLAER---------KNASVAILTTAETYSTALYFTFTSLTSVGFG 473
            |.|...|..:... .|.||..|.::         .::..:|   .:.|.|||||||:||||||||
 Frog   579 YAIGNVERPYLIH-KISWLDALGDQIKKPYNYSDPSSGPSI---KDKYVTALYFTFSSLTSVGFG 639

  Fly   474 NVSANTTAEKVFTIIMMLIGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKEL 538
            |||.||.:||||:|.:||||:||:|.:||||:|||||:||..:.|..:...:|:|:..|.:|..|
 Frog   640 NVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPL 704

  Fly   539 KQRIEDYFQTSWSLSHGIDIYETLREFPEELRGDVSMHLHREILQ-LPIFEAASQGCLKLLSLHI 602
            :||:|:|||.:||.::|||:...|:.|||.|:.|:.:||::.:|| ...|..||:|||:.|::..
 Frog   705 RQRLEEYFQHAWSYTNGIDMNMVLKGFPECLQADICLHLNKTLLQNCKAFSGASKGCLRALAMKF 769

  Fly   603 KTNFCAPGEYLIHKGDALNYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQMTA 667
            ||....||:.|:|.||.|..:|:|..||:|::|||:|||||||.|:.|.  .|||.|...
 Frog   770 KTTHAPPGDTLVHSGDILTALYFLSRGSIEILKDDIVVAILGKNDIFGE--MVHLYAKPG----- 827

  Fly   668 TTNSAGQDVVVRSSSDIKALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDLTCNLREGYEN 732
                       :|.:|::|||||||..|....|:|||.:|||:..||..::  :||.|||:  ||
 Frog   828 -----------KSIADVRALTYCDLHKIQREDLLEVLDMYPEFSDQFLTNL--ELTFNLRD--EN 877

  Fly   733 Q---------DSDI-GPSFPL-------PSISEDDENREEAEEGGKGE----------KENGGGP 770
            .         |.|. |.:..|       .:.|::|.:|:|::.|.:..          |:|....
 Frog   878 SKAALLRSHADIDFNGENCKLRRRKLSFKNKSDEDCSRDESQNGSESSTDDTRNYSSTKKNMDIK 942

  Fly   771 PSGASPLHNISNSPLHATRSPLLGMGS-PRNQRLHQR-------------------------GRS 809
            .||:|........||:...|....:.| |..|:..:.                         .|.
 Frog   943 KSGSSSSSINETKPLYTEISAYTSVFSKPSGQQFEEAVCPSAKLNLGKRSASNKDITGTRSWERE 1007

  Fly   810 LITLRETNKRHRTLN----AACSLDR----GSFEEPEPLEEEQSSGGKRPSLERLDSQVSTLHQD 866
            ...|.::...|..||    ..|..|.    |..|:...|.:||        :.||:.|:::..|.
 Frog  1008 NAVLHDSAPNHSALNHTTWGICEADNDLTYGEMEKRLDLIQEQ--------MNRLELQMTSDIQA 1064

  Fly   867 VAQLSAEVRNAISALQEMTFTS-----------NAMTSHSSLK----FPPARSIPNISGVAGTR- 915
            :.||.....:.|.....|...|           .:|.:.:|:|    |.|:...|.::.:..:|
 Frog  1065 ILQLLQRQSSLIPPAYSMVTASCEYARPTARRVQSMHAKASIKTDRSFSPSSQSPELAELEKSRP 1129

  Fly   916 -------SGV------------AVEHGLMGGVLAAAELAAMQRSSSHPPEVWG--RDVQLPTSNT 959
                   ||.            .|:||         :...::....|.|....  |...||.|:.
 Frog  1130 KSKESLSSGAHLNPTPEDNPAQGVDHG---------QEHPLESQPRHCPSYLNPIRHTSLPDSSV 1185

  Fly   960 AS 961
            .|
 Frog  1186 NS 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS	36..132	CDD:238075	37/95 (39%)
		PAS_3	41..129	CDD:285623	37/87 (43%)
		Ion_trans	285..516	CDD:278921	121/252 (48%)
		Ion_trans_2	<455..510	CDD:285168	40/54 (74%)
		Crp	583..>650	CDD:223736	33/67 (49%)
		CAP_ED	586..715	CDD:237999	55/128 (43%)
kcnh7	XP_031749023.1	PAS_9	29..134	CDD:404329	40/104 (38%)
		Ion_trans	417..679	CDD:395416	126/265 (48%)
		CAP_ED	753..864	CDD:237999	55/128 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247304at2759
OrthoFinder	1	1.000	-	-		FOG0000148
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X71
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920