Protein Alignment Elk and kcnh5

DIOPT Version :10

• Sequence 1: NP_477009.1
• Gene: Elk / 37047
• FlyBaseID: FBgn0011589
• Length: 1284
• Species: Drosophila melanogaster
• Sequence 2: XP_012823505.2
• Gene: kcnh5 / 100151738
• XenbaseID: XB-GENE-1013572
• Length: 1000
• Species: Xenopus tropicalis
• Alignment Length: 1016
• Identity: 325/1016 - (31%)
• Similarity: 510/1016 - (50%)
• Gaps: 170/1016 - (16%)

  Fly     1 MP-ARKGLLAPQNTFLDTIATRFDGTHSNFVLGNAQANGNPIVYCSDGFVDLTGYSRAQIMQKGC 64
            || .::||:|||||||:.|..|  .:.|:|:|||||....|:||.:|||..|:||.||.||||..
 Frog     4 MPGGKRGLVAPQNTFLENIVRR--SSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADIMQKSS 66

  Fly    65 SCHFLYGPDTKEEHKQQIEKSLSNKMELKLEVIFYKKEGAPFWCLFDIVPIKNEKRDVVLFLASH 129
            :|.|:||..|.::..:::.::..|......||:.|||...|.|....|.||:||...|||||.:.
 Frog    67 TCSFMYGELTDKKTIEKVRQTFENYESNCFEVLLYKKSRTPVWFYMQIAPIRNEHEKVVLFLCTF 131

  Fly   130 KDITHTKMLEMNVNEECDSVFALTAALLGARFRAGSNAGMLGLGGLPGLGGPAASDGDTEAGEGN 194
            ||||   :.:..:.:|.      |.|.||.                |.|..|            .
 Frog   132 KDIT---LFKQPIEDES------TRATLGP----------------PPLNNP------------Q 159

  Fly   195 NLDVPAGCNMGRRRSRAVLYQLSGHYKPE----KGGVKTKLKLGNNFMHSTEAPFPEYKTQSIKK 255
            .....|........||:||.||:...|.|    ...:...|:||::.:       |:||.::.|.
 Frog   160 RWTKFARLTRALTNSRSVLQQLTPMNKAEVVHKHSRLAEVLQLGSDIL-------PQYKQEAPKT 217

  Fly   256 SRLILPHYGVFKGIWDWVILVATFYVALMVPYNAAFAKADRQTK-------VSDVIVEALFIVDI 313
            ...|:.||..||..||||||:.|||.|:|||||.:|     :||       |.|.:|:.:|:|||
 Frog   218 PPHIILHYCAFKTTWDWVILILTFYTAIMVPYNVSF-----KTKQNNIAWLVLDSVVDVIFLVDI 277

  Fly   314 LLNFRTTFVSRKGEVVSNSKQIAINYLRGWFALDLLAALPFDHLYASDLYD-GEDSHIHLVKLTR 377
            :|||.||||...|||:|:.|.|.:|||:.||.:|||:.||:|.:.|.:..| |..|....:|:.|
 Frog   278 VLNFHTTFVGPGGEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGMSSLFSSLKVVR 342

  Fly   378 LLRLARLLQKIDRYSQHTAMILTLLMFSFTLAAHWLACIWYVIAVKEYEWFPE-----SNIGWLQ 437
            ||||.|:.:|:|.|.::.|.:|.||:..|.|.|||||||||  ::.:||...|     ....||.
 Frog   343 LLRLGRVARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWY--SIGDYEVIDEVTNTIKKDSWLY 405

  Fly   438 LLA------ERKNASVAIL-----TTAETYSTALYFTFTSLTSVGFGNVSANTTAEKVFTIIMML 491
            .|.      .|.|||.:..     :....|.::||||.||||::||||::..|..||:|::.||:
 Frog   406 QLGLSIGTPYRYNASGSGQWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDGEKIFSVAMMM 470

  Fly   492 IGALMHAVVFGNVTAIIQRMYSRRSLYESKWRDLKDFVALHNMPKELKQRIEDYFQTSWSLSHGI 556
            :|:|::|.:|||||.|.|:||:..:.|.....:::||:.|:.:||.|.:|:.||..::||:|.||
 Frog   471 VGSLLYATIFGNVTTIFQQMYANTNRYHEVLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGI 535

  Fly   557 DIYETLREFPEELRGDVSMHLHREIL-QLPIFEAASQGCLKLLSLHIKTNFCAPGEYLIHKGDAL 620
            |..:.|...|:::|.|:.:||:|::. :.|.|..||.|||:.|::..:|..||||:.:.|.|:::
 Frog   536 DTEKVLGICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRSLAVEFQTIHCAPGDLIYHAGESV 600

  Fly   621 NYIYYLCNGSMEVIKDDMVVAILGKGDLVGSDINVHLVATSNGQMTATTNSAGQDVVVRSSSDIK 685
            :.:.::.:||:|||:|:.|||||||||:.|   :|....|:               :..:.::::
 Frog   601 DALCFVVSGSLEVIQDEEVVAILGKGDVFG---DVFWKETT---------------LAHACANVR 647

  Fly   686 ALTYCDLKCIHMGGLVEVLRLYPEYQQQFANDIQHDLTCNLR---------------EGYENQDS 735
            |||||||..|....|::||..|..:...|:.::  .||||||               |..:.|.:
 Frog   648 ALTYCDLHIIKREALLKVLDFYTAFANSFSRNL--TLTCNLRKRIVFRKISDVKKEEEERQRQKN 710

  Fly   736 DIGPSFPL--------PSISEDDENREEAEEGGKGEKE---------NGGGPPSGASPLHNISNS 783
            ::..|.|:        ....:..|.|.:.......|:.         :.|...:|.|.:.....:
 Frog   711 EVTLSIPVDHPVRKLFQKFKQQKELRNQGSTNSDLERNQLQVEHRSMHNGAVLTGTSVVTVSQIT 775

  Fly   784 PLHATRSPLLGMGSPRNQRLHQRGRSLITLRETNKRHRTLNAACSLDRGSFEEPEPLEEEQSSGG 848
            |:..:.|.:               |:..:|::.|:....|..:.|.|..|.:...|:..:..:|.
 Frog   776 PIQTSLSYV---------------RTNESLKQNNRDAMELKPSSSSDTKSLKVTSPVRLKNGNGK 825

  Fly   849 KRPSLERLDSQVSTLHQDVAQLSAEVRNAISALQEMTFTSN---AMTSHSSLKFPPARSIPNI-S 909
            ....|:.        :..|.:...|..|.::..:.:...|:   .....|::...|.|...:. |
 Frog   826 GWLKLKN--------NMQVQEEKKEDWNNVTKAESLGLLSDDPKCTDPESNVSKNPLRKTDSCDS 882

  Fly   910 GVAGTRSGVAVEHGLMGGVLAAAELAAMQRSSSHP----PE 946
            |:  |:|.:.::..  |...:..|.:.:|..:.||    ||
 Frog   883 GI--TKSDLRLDKA--GETRSPLEHSPLQADAKHPFYPIPE 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elk	NP_477009.1	PAS_9	40..133	CDD:463873	40/92 (43%)
		PLN03192	270..>650	CDD:215625	172/404 (43%)
		cNMP	586..716	CDD:197516	45/129 (35%)
kcnh5	XP_012823505.2	PAS_9	42..135	CDD:463873	40/92 (43%)
		PLN03192	232..>632	CDD:215625	173/409 (42%)
		Crp	567..>717	CDD:440428	54/169 (32%)