DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mapmodulin and anp32c

DIOPT Version :9

Sequence 1:	NP_001097361.1	Gene:	Mapmodulin / 37043	FlyBaseID:	FBgn0034282	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_989404.1	Gene:	anp32c / 395041	XenbaseID:	XB-GENE-991758	Length:	242	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	121/356 - (33%)
Similarity:	166/356 - (46%)	Gaps:	123/356 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKRIELERRARKVNQITELNLDNCRST--SIVGLTDEYTALESLSLINVGLTTLKGFPKLPNLK 63
            |:||:.||.|.||...:.||.||||||.  .|:|||.|:..||.||:|||.|.::...||||.||
Frog     3 MKKRLMLELRNRKAADVKELVLDNCRSDDGKIIGLTSEFENLEFLSMINVNLLSVANLPKLPKLK 67

  Fly    64 KLELSDNRISSGLNYLT-TSPKLQYLNLSGNKIKDLETLKPLEEFKNLVVLDLFNNDATQVDNYR 127
            ||||||||||.||..|. .:|.|.:|||||||||::.||:||::..:|:.|||||.:.|.::|||
Frog    68 KLELSDNRISGGLEVLAERTPNLTHLNLSGNKIKEINTLEPLKKLPHLMSLDLFNCEVTMLNNYR 132

  Fly   128 EKIFKMLPSLNFLDGFDCNDEEVQSDGDDDDEVNGNDSDEVGDKCNAFCLNGLEIDLDELEAFEK 192
            |.:|::||.|.||||||.:|:|..            |||
Frog   133 ESVFELLPQLTFLDGFDADDQEAP------------DSD-------------------------- 159

  Fly   193 RVKAKKSLQDKPPPQSEDKEVDELDEYLKELQLRESTDASTDEQSVINATPQPPSNSNLSFVILL 257
                         |::||     |:|
Frog   160 -------------PEAED-----LEE--------------------------------------- 167

  Fly   258 YWFLAILNLGSATYFSDEDDDSDDSDEEANGEVSLSEVYNDDLEEDNSDWEGEDEAGEEDEEEDS 322
                           :.||.:.|:.|||.         :.|:|:::..|.|||||.|||:||.|.
Frog   168 ---------------NGEDGEDDEEDEEE---------FEDELDDEEDDEEGEDEEGEEEEEGDE 208

  Fly   323 DIDDADGDANESAASVNAKDKDGEKEADESQ 353
            : |:.|.|..:........:.||::|.|:.:
Frog   209 E-DEDDEDVPQGEKRKRDLEDDGDEEDDDDE 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mapmodulin	NP_001097361.1	leucine-rich repeat	17..39	CDD:275380	13/23 (57%)
		LRR_4	38..74	CDD:289563	23/35 (66%)
		LRR_8	40..95	CDD:290566	35/55 (64%)
		leucine-rich repeat	40..61	CDD:275380	11/20 (55%)
		LRR_4	60..103	CDD:289563	29/43 (67%)
		leucine-rich repeat	62..84	CDD:275380	15/22 (68%)
		LRR_4	83..125	CDD:289563	22/41 (54%)
		leucine-rich repeat	85..109	CDD:275380	14/23 (61%)
		leucine-rich repeat	110..136	CDD:275380	13/25 (52%)
anp32c	NP_989404.1	LRR 1	18..38		10/19 (53%)
		LRR 2	43..64		10/20 (50%)
		LRR 3	65..87		15/21 (71%)
		LRR_9	<71..146	CDD:317038	41/74 (55%)
		LRR 4	89..110		13/20 (65%)
		leucine-rich repeat	90..113	CDD:275382	14/22 (64%)
		leucine-rich repeat	115..141	CDD:275382	13/25 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	148..242		39/211 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	211	1.000	Inparanoid score	I3564
OMA	1	1.010	-	-		QHG59800
OrthoDB	1	1.010	-	-		D1622194at2759
OrthoFinder	1	1.000	-	-		FOG0001011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11375
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2396
SonicParanoid	1	1.000	-	-		X672
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.200