Protein Alignment CG14490 and Als2

DIOPT Version :10

• Sequence 1: NP_611274.1
• Gene: CG14490 / 37041
• FlyBaseID: FBgn0034281
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_082993.4
• Gene: Als2 / 74018
• MGIID: 1921268
• Length: 1651
• Species: Mus musculus
• Alignment Length: 180
• Identity: 51/180 - (28%)
• Similarity: 79/180 - (43%)
• Gaps: 30/180 - (16%)

  Fly     3 SRTSGYSSGVRSQRYPGGQYQGKWLGQQPHGFGVKQTSSGLVYEGHWQKGQRHGIGSLRRKELDG 67
            ||::.|:. .:..|.....|.|:||..:|||.||.:...|.:|.|.::.|...|.|..|......
Mouse  1025 SRSAKYTF-YKDTRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAL 1088

  Fly    68 RMERIYVGQWRENKRSGEGKQFYPDGSVYFGQWLADQRSGEGI-----LWQADGGIYVGEWLRDK 127
            ..|..|||.|:|.|..|:|...|..|.|:.|.:..:.|.|.|:     |..:...:::|:|:.||
Mouse  1089 NKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDK 1153

  Fly   128 MHEKGLLFTATGNRYVGQFEGGCKSGSGVFYHASNGQRIQHGFWSKDICR 177
                                   |:|.|||...:.|::.. |.|..|:|:
Mouse  1154 -----------------------KAGYGVFDDITRGEKYM-GMWQDDVCQ 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14490	NP_611274.1	COG4642	<18..173	CDD:443680	45/159 (28%)
Als2	NP_082993.4	ATS1	<18..219	CDD:444065
		RCC1 1. /evidence=ECO:0000305	59..108
		RCC1 2. /evidence=ECO:0000305	109..167
		RCC1 3. /evidence=ECO:0000305	169..218
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..462
		RCC1 4. /evidence=ECO:0000305	519..570
		ATS1	<521..622	CDD:444065
		RCC1 5. /evidence=ECO:0000305	572..621
		RhoGEF	689..873	CDD:470622
		PH_alsin	899..1004	CDD:241423
		COG4642	<1012..1243	CDD:443680	51/180 (28%)
		MORN 1	1043..1065		10/21 (48%)
		MORN 2	1066..1088		6/21 (29%)
		MORN 3	1094..1116		10/21 (48%)
		MORN 4	1117..1139		5/21 (24%)
		MORN 5	1145..1167		9/44 (20%)
		MORN 6	1169..1191		4/12 (33%)
		MORN 7	1192..1214
		MORN 8	1215..1238
		VPS9	1546..1650	CDD:460489