DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14490 and JPH1

DIOPT Version :9

Sequence 1:	NP_611274.1	Gene:	CG14490 / 37041	FlyBaseID:	FBgn0034281	Length:	197	Species:	Drosophila melanogaster
Sequence 2:	NP_001304759.1	Gene:	JPH1 / 56704	HGNCID:	14201	Length:	661	Species:	Homo sapiens

Alignment Length:	189	Identity:	53/189 - (28%)
Similarity:	78/189 - (41%)	Gaps:	49/189 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GYSSGVRSQRYPGGQYQGKWLGQQPHGF---GVKQTSSGLVYEGHWQKGQRHGIGSLRRKELDGR 68
            |..:|.:.|    |:|.|.|    .|||   |.....||..|:|:|.:|:|||:|    .|..|:
Human    27 GICTGPKGQ----GEYSGSW----SHGFEVVGGYTWPSGNTYQGYWAQGKRHGLG----VETKGK 79

  Fly    69 MERIYVGQWRENKRSGEG-KQFYPDGSVYFGQWLADQRSGEGILWQADGGIYVGEWLRDKMHEKG 132
            .  :|.|:|....:...| :|.....:.|.|.|....:.|.|:....|||.|.|:|
Human    80 W--MYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQW--------- 133

  Fly   133 LLFTATGNRYVGQFEGGCKSGSGVFYHASNGQRIQHGFWS--KDICRTSLLSLPQDKNN 189
                          .||.:.|.||      .|.:.:|..:  :...||||.||..:::|
Human   134 --------------AGGMRHGYGV------RQSVPYGMATVIRSPLRTSLASLRSEQSN 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14490	NP_611274.1	COG4642	35..170	CDD:226989	35/135 (26%)
JPH1	NP_001304759.1	PLN03185	4..>143	CDD:215619	42/152 (28%)
		MORN 1	14..36		3/12 (25%)
		MORN 2	38..59		9/24 (38%)
		MORN 3	60..82		10/27 (37%)
		PLN03185	106..>325	CDD:215619	25/96 (26%)
		MORN 4	106..128		7/21 (33%)
		MORN 5	129..151		9/50 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	228..247
		MORN 6	281..303
		MORN 7	304..326
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	433..631
		TonB	<434..>528	CDD:223880
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900