DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14490 and Als2

DIOPT Version :9

Sequence 1:NP_611274.1 Gene:CG14490 / 37041 FlyBaseID:FBgn0034281 Length:197 Species:Drosophila melanogaster
Sequence 2:NP_001013431.1 Gene:Als2 / 363235 RGDID:1310372 Length:1651 Species:Rattus norvegicus


Alignment Length:221 Identity:62/221 - (28%)
Similarity:91/221 - (41%) Gaps:37/221 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 SRTSGYSSGVRSQRYPGGQYQGKWLGQQPHGFGVKQTSSGLVYEGHWQKGQRHGIGSLRRKELDG 67
            ||::.|:. .:..|.....|.|:||..:|||.||.:...|.||.|.::.|...|.|..|......
  Rat  1025 SRSAKYTF-YKDTRLKDATYDGRWLSGKPHGRGVLKWPDGKVYSGTFRNGLEDGYGEYRIPNKAL 1088

  Fly    68 RMERIYVGQWRENKRSGEGKQFYPDG----------------------------SVYFGQWLADQ 104
            ..|..|||.|:|.|..|:|...|..|                            |::.|||:.|:
  Rat  1089 NKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDK 1153

  Fly   105 RSGEGILWQ-ADGGIYVGEWLRDKMHEKGLLFTATGNRYVGQFEGGCKSGSGVFYHASNGQRIQH 168
            ::|.|:... ..|..|:|.|..|.....|::.|..|..|.|.|......|:||.  .|....|..
  Rat  1154 KAGYGVFDDITRGEKYMGMWQDDACQGNGVVVTQFGLYYEGNFHLNKMMGNGVL--LSEDDTIYE 1216

  Fly   169 GFWSKD--ICRTSLLSLPQDKNNEFM 192
            |.:|.|  :|....|::|   |.:::
  Rat  1217 GEFSDDWTLCGKGTLTMP---NGDYI 1239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14490NP_611274.1 COG4642 35..170 CDD:226989 44/163 (27%)
Als2NP_001013431.1 RCC1 1 59..108
RCC1_2 93..122 CDD:290274
RCC1 2 109..167
RCC1 109..165 CDD:278826
RCC1 3 169..218
RCC1 170..216 CDD:278826
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 444..476
RCC1 4 519..570
RCC1 521..568 CDD:278826
RCC1 5 572..621
RCC1 573..619 CDD:278826
RhoGEF 689..873 CDD:295373
PH_alsin 899..1004 CDD:241423
PH 920..998 CDD:278594
COG4642 1043..1182 CDD:226989 40/138 (29%)
MORN 1 1043..1065 10/21 (48%)
MORN 1043..1063 CDD:280628 9/19 (47%)
MORN 2 1066..1088 6/21 (29%)
MORN 3 1094..1116 10/21 (48%)
MORN 1094..1114 CDD:280628 9/19 (47%)
MORN 4 1117..1139 0/21 (0%)
MORN 5 1145..1167 6/21 (29%)
COG4642 1166..>1266 CDD:226989 23/79 (29%)
MORN 6 1169..1191 7/21 (33%)
MORN 7 1192..1214 7/23 (30%)
MORN 8 1215..1238 7/25 (28%)
VPS9 1548..1647 CDD:280383
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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