Protein Alignment Orai and orai2

DIOPT Version :10

• Sequence 1: NP_001137696.1
• Gene: Orai / 37040
• FlyBaseID: FBgn0041585
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_005165627.1
• Gene: orai2 / 555612
• ZFINID: ZDB-GENE-060531-127
• Length: 281
• Species: Danio rerio
• Alignment Length: 265
• Identity: 125/265 - (47%)
• Similarity: 157/265 - (59%)
• Gaps: 50/265 - (18%)

  Fly   269 QQNQSYRFQ-----PRGHHRTASSSMSQSGEDL------------------HSPTYLSWRKLQLS 310
            :|:||....     |.|......|...|.|..:                  ||...||||||.||
Zfish     8 RQSQSATMSSELTVPMGSPAPGGSDRLQDGGGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLS 72

  Fly   311 RAKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAICTTLLVAVHMLALMISTCILPN 375
            ||||||||:||||||||||||||||||:...|.|..:||||::|||:|||||:.||:||||||||
Zfish    73 RAKLKASSRTSALLSGFAMVAMVEVQLEMQYNYPRVLLIAFSVCTTVLVAVHLFALLISTCILPN 137

  Fly   376 IETVCNLHSISLVHESPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKF------------- 427
            :|.|.|:|:::.|.||||||:|.|||.||.|||.||::|||.|:.:|||:||
Zfish   138 VEAVSNIHNLNSVSESPHERMHHYIELAWGFSTALGILLFLAEVVLLCWIKFLPVDSGAQSASAL 202

  Fly   428 ----YDLSPPA------AWSAC----VVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEML 478
                .:.|.||      .|.|.    ::::||.:||:.|.||||||||.||.|.....|.||..:
Zfish   203 VALKQNCSTPAVQPGHSGWQAALASTIIMVPVGLIFVVFTIHFYRSLVRHKTERHHQEIEELHKI 267

  Fly   479 KEQME 483
            |.|::
Zfish   268 KVQLD 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orai	NP_001137696.1	Orai-1	301..466	CDD:462291	109/191 (57%)
orai2	XP_005165627.1	Orai-1	63..255	CDD:462291	109/191 (57%)