Protein Alignment Orai and orai1b

DIOPT Version :10

• Sequence 1: NP_001137696.1
• Gene: Orai / 37040
• FlyBaseID: FBgn0041585
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_991163.1
• Gene: orai1b / 402892
• ZFINID: ZDB-GENE-050522-100
• Length: 222
• Species: Danio rerio
• Alignment Length: 224
• Identity: 125/224 - (55%)
• Similarity: 161/224 - (71%)
• Gaps: 17/224 - (7%)

  Fly   289 MSQSGEDLHSPTYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAI 353
            ||:|.   ||...||||||.||||||||||:|||||||||||||||||||.:.:.|||:||||:.
Zfish     3 MSRSE---HSLQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTNHDYPPGLLIAFSA 64

  Fly   354 CTTLLVAVHMLALMISTCILPNIETVCNLHSISLVHESPHERLHWYIETAWAFSTLLGLILFLLE 418
            |||:|||||:.|||:|||||||||.|.|:|:::.|.||||||:|.:||.||||||::|.:|||.|
Zfish    65 CTTVLVAVHLFALMVSTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAE 129

  Fly   419 IAILCWVKFYDLSP------------PAAWSACVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSG 471
            :.:||||||..:.|            .||.::..:::|..::|:.||:||||||||||.:.....
Zfish   130 VVLLCWVKFLPIKPKDQKNGTVSAGVAAAITSTSIMVPFGLVFIVFAVHFYRSLVSHKTDRQFQE 194

  Fly   472 IRELEMLKEQMEQDHLEHHNNIRNNGMNY 500
            :.|||.|  |.|.||.|..:.:::.|..|
Zfish   195 LEELEDL--QNELDHREEVSTLQSPGSLY 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orai	NP_001137696.1	Orai-1	301..466	CDD:462291	109/176 (62%)
orai1b	NP_991163.1	Orai-1	12..189	CDD:462291	109/176 (62%)