Protein Alignment Orai and Orai3

DIOPT Version :10

• Sequence 1: NP_001137696.1
• Gene: Orai / 37040
• FlyBaseID: FBgn0041585
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001014046.1
• Gene: Orai3 / 309000
• RGDID: 1306538
• Length: 290
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 123/299 - (41%)
• Similarity: 166/299 - (55%)
• Gaps: 80/299 - (26%)

  Fly   243 APLAPLASIASPPFAAQPPPFQLRTYQQNQSYRFQPRGHHRTASSSMSQSGEDLHSPTYLSWRKL 307
            |||.|  .:.||..:|        ||::     |..||:       :...|...||...||||:|
  Rat    12 APLNP--EVDSPAGSA--------TYRE-----FVHRGY-------LDLMGASQHSLRALSWRRL 54

  Fly   308 QLSRAKLKASSKTSALLSGFAMVAMVEVQLDHDTNVPPGMLIAFAICTTLLVAVHMLALMISTCI 372
            .||||||||||:||||||||||||||||||:.|...|||:|:||:.|||:|||||:.|||:|||:
  Rat    55 YLSRAKLKASSRTSALLSGFAMVAMVEVQLESDHEYPPGLLVAFSACTTVLVAVHLFALMVSTCL 119

  Fly   373 LPNIETVCNLHSISLVHESPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSPP---- 433
            ||:||.|.|:|:::.||:|||:|||.|:|.||.|||.||..|||.|:.::.||||..:..|
  Rat   120 LPHIEAVSNIHNLNSVHQSPHQRLHRYVELAWGFSTALGTFLFLAEVVLVGWVKFVPIGAPMDKP 184

  Fly   434 ------------------------------------------------------AAWSACVVLIP 444
                                                                  ||.::..:::|
  Rat   185 APVVPMSQVPPVTVSLSLASNLTPSSASVATTQQPPKACPPRQVCGSAHGPGWQAAMASTAIMVP 249

  Fly   445 VMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQME 483
            |.::|||||:|||||||:||.:.....:.||..|:.:::
  Rat   250 VGLVFMAFALHFYRSLVAHKTDRHKQELEELSRLQGELQ 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orai	NP_001137696.1	Orai-1	301..466	CDD:462291	105/222 (47%)
Orai3	NP_001014046.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		4/10 (40%)
		Orai-1	48..271	CDD:462291	105/222 (47%)