DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment olf186-M and Tespa1

DIOPT Version :9

Sequence 1:	NP_611272.1	Gene:	olf186-M / 37039	FlyBaseID:	FBgn0015522	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_899087.2	Gene:	Tespa1 / 67596	MGIID:	1914846	Length:	458	Species:	Mus musculus

Alignment Length:	210	Identity:	57/210 - (27%)
Similarity:	85/210 - (40%)	Gaps:	43/210 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SVHFPPSKPLRRRRKLQRQQSAVDTDDMEYAADLEENADP------DAHEHMSPVVTMP--MRHI 91
            ||..|.|...||....|.:.......:.|.||.|::..||      |..:..:|:..:.  ::..
Mouse     4 SVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDALDPEPSSLDDVFQEGNPINKIEDWLQGC 68

  Fly    92 SATSTRCLRHEESFES---------SSTAPELSPQAQ----------------RQQRFSSLLLRD 131
            ....|.....|||.:|         :|...:||..|:                :..|...||...
Mouse    69 GCRDTEEGLSEESGQSNYSGYSSHGTSFEDDLSLGAEATLLSTNGNLFSRNFLQTPRLCQLLDLG 133

  Fly   132 SSVSVQS----DSSRYSSVDSLLEARKPDPEAILINLGFGPLSSEDMLSRIPRRFL-KPSQVPGI 191
            ||::..|    .:...||:..:|:..:.|.|.||.:||||..:.:| .||||.||. .|||..||
Mouse   134 SSLASSSMTGGTNKTSSSISEILDQVQEDAEDILFSLGFGHENHKD-TSRIPARFFSNPSQAKGI 197

  Fly   192 DTDAF----VQRLTL 202
            :...|    |||:.:
Mouse   198 NFQLFLKSQVQRMEM 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
olf186-M	NP_611272.1	KRAP_IP3R_bind	144..>200	CDD:291392	26/60 (43%)
Tespa1	NP_899087.2	KRAP_IP3R_bind	130..251	CDD:373246	31/84 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..356
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005638
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000