DRSC/TRiP Functional Genomics Resources

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Protein Alignment olf186-M and ITPRID2

DIOPT Version :9

Sequence 1:NP_611272.1 Gene:olf186-M / 37039 FlyBaseID:FBgn0015522 Length:254 Species:Drosophila melanogaster
Sequence 2:NP_001123917.1 Gene:ITPRID2 / 6744 HGNCID:11319 Length:1259 Species:Homo sapiens


Alignment Length:302 Identity:67/302 - (22%)
Similarity:105/302 - (34%) Gaps:93/302 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 RRRR---KLQRQQSAVDTDDMEYAA---DLEENADPDAHEHMSPVV----TMPMRHISATSTRC- 98
            |||:   |.:....|.:|:|:...|   |.||:.:.|......|..    .:|...|:.....| 
Human    22 RRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLPGAQLPAAGGRGNVPNEKIAIWLKDCR 86

  Fly    99 -------------------LRHEESFES----SSTAPELSPQAQRQQRFSSLLLRD--------- 131
                               :|:..|||.    .:.|..|.....:.:..:::|.::         
Human    87 TPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGAEANHLHESDAQIENCNNILAKERRLQFHQKG 151

  Fly   132 ---SSVSVQSDSSRYSSVDSLLEARKPDPEAILINLGFGPLSSEDMLSRIPRRFLKPSQ-VPGID 192
               :|......|...|||..|||..:.|||.||.||||| ....|:.|:||.||...|. ..|||
Human   152 RSMNSTGSGKSSGTVSSVSELLELYEEDPEEILYNLGFG-RDEPDIASKIPSRFFNSSSFAKGID 215

  Fly   193 TDAFV--------------------QRLTLARSLADSSVLGYRGLTGNP---------------- 221
            ...|:                    :::.:..::|::....|..::|.|                
Human   216 IKVFLSAQMQRMEVENPNYALTSRFRQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKET 280

  Fly   222 DMPP----SSIVASIMKRFE-----VNHHRKNSMGSIKPSIQ 254
            |.||    |:....:||...     |:...|....|..||.:
Human   281 DPPPPLTRSNTANRLMKTLSKLNLCVDKTEKGESSSPSPSAE 322

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
olf186-MNP_611272.1 KRAP_IP3R_bind 144..>200 CDD:291392 27/76 (36%)
ITPRID2NP_001123917.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..72 9/40 (23%)
KRAP_IP3R_bind 148..298 CDD:291392 38/150 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 268..290 3/21 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 306..450 5/17 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 806..829
SSFA2_C 866..1017 CDD:291393
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1094..1137
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1154..1215
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0005638
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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