Protein Alignment grh and grhl3

DIOPT Version :9

• Sequence 1: NP_476845.2
• Gene: grh / 37038
• FlyBaseID: FBgn0259211
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: XP_021323102.1
• Gene: grhl3 / 794613
• ZFINID: ZDB-GENE-030131-9854
• Length: 590
• Species: Danio rerio
• Alignment Length: 554
• Identity: 178/554 - (32%)
• Similarity: 265/554 - (47%)
• Gaps: 100/554 - (18%)

  Fly   801 PSPDSGIGTDAITPRD---QTNIQQSFDYTELCQPG--------TLIDANGSIPVSVNSIQQRTA 854
            ||..|   ||:.|..:   |.|:...|| :.|.||.        |.::|
Zfish   113 PSKPS---TDSYTTDNYDKQVNLNNIFD-SLLPQPSQKSWQSDQTFLEA---------------- 157

  Fly   855 VHGSQNSPTTSLVDTSTNGSTRSRPWHDFGRQND---ADKIQIPKIFTNVGFRYHLESPISSSQR 916
                  :|...:.....||         ||.|..   :|....|..:.| .|::.|.:|.:|..:
Zfish   158 ------TPEVRIYHIGHNG---------FGGQTSPVYSDSYSSPGRYRN-DFQFLLGAPQASQHK 206

  Fly   917 REDDRITYINKGQFYGITLEYVHDAEKPIKNTTVKSVIMLMFREEKSPEDEIKAWQFWHSRQHSV 981
            ..:..:.|:||||||.|||:.| |:...:..:.||:|||.:|..:||||.::|.|..||:||.:|
Zfish   207 TTEIPMVYLNKGQFYPITLQGV-DSTAGVPCSKVKTVIMAVFENDKSPEMQLKYWNHWHARQPTV 270

  Fly   982 KQRILD-ADTKNSVGLVGCIEEVSHNAIAVYWNPLESSAKINIAVQCLSTDFSSQKGVKGLPLHV 1045
            |||::| ||.|.....|..:|||:.||::..||..| .||::|.:..||||||||||||||||::
Zfish   271 KQRVIDIADYKEVFSGVSNVEEVAFNALSFIWNTNE-EAKVHIGINSLSTDFSSQKGVKGLPLNL 334

  Fly  1046 QIDTFE-DPRDTAVFHRGYCQIKVFCDKGAERKTRDEERRAAKRKMTATGRKKLDELYHPVT--- 1106
            ||||:: ...:..:.||..||:|:|||||||||.|||||:.:||:...|.....:.....:.
Zfish   335 QIDTYDFSSGNNRLIHRAVCQVKIFCDKGAERKMRDEERKRSKRRTKNTADSSNNNCKQALVSSS 399

  Fly  1107 ---DRSEFYGMQDFAKPPVLFSPAEDMEKVGQLGIGAATGMTFNPLSNGNSNSNSHSSLQSF--Y 1166
               |.:.|..:.|....||||.|......:.:.|:       ..|:|...|:   .|||:.:  .
Zfish   400 VGKDSTYFKTLDDHVTQPVLFIPEMHFSTMQRCGL-------VPPVSLEESD---RSSLKRYADA 454

  Fly  1167 GHETDSPDLKGASPFLLHGQKVATPTLKFHNHFPPDMQTDKKDHILDQNMLTSTPLTDFGPPMKR 1231
            ..::.||..|........|:...:..::....|.|            .::|.   :..|.|
Zfish   455 NEQSSSPPCKQPRRDEQRGRGEVSNQIRDAGIFQP------------HSVLI---VNSFFP---- 500

  Fly  1232 GRMTPPTSERVMLYVRQENEEVYTPLHVVPPTTIGLLNAIENKYKISTTSINNIYRTNKKGITAK 1296
                     .|:||||:|:|||:..|.:..|...||..||..||.:...:|..|::..|:||...
Zfish   501 ---------AVLLYVRRESEEVFDALMLNTPNLKGLKEAISEKYGMQEDTIGKIFKKCKRGIFVN 556

  Fly  1297 IDDDMISFYCNEDIFLLEVQQIEDDLYDVTLTEL 1330
            :||::|..|.|...||:|:.::..:.|.|||.||
Zfish   557 MDDNIIEHYSNHSAFLIEISEVIVNHYQVTLMEL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grh	NP_476845.2	CP2	903..1089	CDD:282385	92/187 (49%)
grhl3	XP_021323102.1	CP2	172..381	CDD:309593	98/211 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3008
eggNOG	1	0.900	-	-		E1_KOG4091
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001445
OrthoInspector	1	1.000	-	-		otm24628
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11037
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X907
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.910