Protein Alignment grh and UBP1

DIOPT Version :9

• Sequence 1: NP_476845.2
• Gene: grh / 37038
• FlyBaseID: FBgn0259211
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_001121633.1
• Gene: UBP1 / 7342
• HGNCID: 12507
• Length: 540
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 120/542 - (22%)
• Similarity: 210/542 - (38%)
• Gaps: 131/542 - (24%)

  Fly   881 HDF-------------GRQNDADKIQIPKIF-------------TNVGFRYHLESPISSSQRRED 919
            |||             |..:.:|.:.:| ||             .:..|:|.:.:..|.:.:..|
Human    17 HDFDASLSGIGQELGAGAYSMSDVLALP-IFKQEDSSLPLDGETEHPPFQYVMCAATSPAVKLHD 80

  Fly   920 DRITYINKGQFYGI-TLEYVHDAEKP-IKNTTVKSVIMLMFREEK---SPEDEIKAWQFWHSRQH 979
            :.:||:|:||.|.| .|:.....:.| |....|||:|.::|.:.:   :...:::.|: |    :
Human    81 ETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLEGWK-W----N 140

  Fly   980 SVKQRILDADTKNSVGLVGCIEEVSH-NAIAVYWNPLESSAKINIAVQCLSTDFSSQK--GVKGL 1041
            ....|:||.|...|||::......|. ||:...|:|.:.::.. |.|.|:||:|:.:|  |.||:
Human   141 RPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAF-IQVHCISTEFTPRKHGGEKGV 204

  Fly  1042 PLHVQIDTF---EDPRDTAVFHRGYCQIKVFCDKGAERKTRDEERRAAKRKMTATGRKKLDELY- 1102
            |..:|:|||   |:...|...|...||||||..|||:||.:.:..:..||  ||..::|....|
Human   205 PFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKR--TAHEKEKYQPSYD 267

  Fly  1103 ---------HPVTDRSEFYGMQDFAKPPVLFSPAEDMEKVGQLGI-----GAATGMTFNPLSNGN 1153
                     .|:.:.:..:..:..:|..:   ||:..:.:.:.|.     .|.|....|..|...
Human   268 TTILTEMRLEPIIEDAVEHEQKKSSKRTL---PADYGDSLAKRGSCSPWPDAPTAYVNNSPSPAP 329

  Fly  1154 SNSNSHSSLQSFYGHETDSPDLKGASPFLLHGQKV------------------ATPTLKFHNHFP 1200
            :.::...|..|.....:.||:.:|.......|:::                  ::.|..|.|...
Human   330 TFTSPQQSTCSVPDSNSSSPNHQGDGASQTSGEQIQPSATIQETQQWLLKNRFSSYTRLFSNFSG 394

  Fly  1201 PDMQTDKKDHILD----------QNMLTSTPLTDFGPPMKRGRMTPPTSERVMLYVRQENEE--- 1252
            .|:....|:.::.          .|.|.|             |...|   |:.:||.:|...
Human   395 ADLLKLTKEDLVQICGAADGIRLYNSLKS-------------RSVRP---RLTIYVCREQPSSTV 443

  Fly  1253 --------------------VYTPLHVVPPTTIGLLNAIENKYKISTTSINNIYRTNKKGITAKI 1297
                                ||..:::.......:...:...:.|....||.:||....||...:
Human   444 LQGQQQAASSASENGSGAPYVYHAIYLEEMIASEVARKLALVFNIPLHQINQVYRQGPTGIHILV 508

  Fly  1298 DDDMISFYCNEDIFLLEVQQIE 1319
            .|.|:..:.:|..||....:.|
Human   509 SDQMVQNFQDESCFLFSTVKAE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grh	NP_476845.2	CP2	903..1089	CDD:282385	63/196 (32%)
UBP1	NP_001121633.1	CP2	54..254	CDD:282385	62/205 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..270		11/35 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..368		14/85 (16%)
		SAM_LBP1	369..435	CDD:188987	12/81 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4091
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810