Protein Alignment grh and Tfcp2l1

DIOPT Version :10

• Sequence 1: NP_476845.2
• Gene: grh / 37038
• FlyBaseID: FBgn0259211
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_001100640.1
• Gene: Tfcp2l1 / 304741
• RGDID: 1305456
• Length: 479
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 129/511 - (25%)
• Similarity: 208/511 - (40%)
• Gaps: 102/511 - (19%)

  Fly   880 WH----DFGRQNDAD-----------KIQIPKIFTNVGFR-----YHLESPISSSQRREDDRITY 924
            ||    .:.:.|...           |.:.|::....|.|     |.|.:..|.:.:..::.:||
  Rat     4 WHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENGARLPPLQYVLCAATSPAVKLHEETLTY 68

  Fly   925 INKGQFYGITL---EYVHDAEKPIKNTTVKSVIMLMFREEKSPEDEIKAWQFWHSRQHSVKQRIL 986
            :|:||.|.|.|   ..:.|.: .:....|||:|.::|.:.:....|.:..:.|  |......|||
  Rat    69 LNQGQSYEIRLLENRKLGDFQ-DLNTKYVKSIIRVVFHDRRLQYTEYQQLEGW--RWSRPGDRIL 130

  Fly   987 DADTKNSVGLVG-CIEEVSHNAIAVYWNPLESSAKINIAVQCLSTDFSSQK--GVKGLPLHVQID 1048
            |.|...|||::. .......||:...|:|.:.::.. |.|.|:||:|:.:|  |.||:|..||||
  Rat   131 DIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAF-IQVHCISTEFTPRKHGGEKGVPFRVQID 194

  Fly  1049 TF---EDPRDTAVFHRGYCQIKVFCDKGAERKTRDEERRAAKRKMTATGRKKLDELYHP--VTDR 1108
            ||   |:...|...|...||||||..|||:||.:.:..:..||  ||..::|....|..  :|:.
  Rat   195 TFKQNENGEYTEHLHSASCQIKVFKPKGADRKQKTDREKMEKR--TAQEKEKYQPSYETTILTEC 257

  Fly  1109 SEF----YGMQDFAKPPVLFSPAEDMEKVGQLGIGAATGMTFNPLSNGNSNSNSH--SSLQSFYG 1167
            |.:    |.......|....||:                 :|. |..|||:.| |  ..|.....
  Rat   258 SPWPDVPYQANSTPSPSYNGSPS-----------------SFG-LREGNSSPN-HPVEPLPLGSD 303

  Fly  1168 HETDSPDLKGASPFLLHGQKVATPTLKFHNHFPPDMQTDKKDHILDQNMLTSTPLTDFGPP---- 1228
            |...|..::.|..: ||..:.:.....|.:....|:....:|.::..          .||.
  Rat   304 HLLPSASIQDAQQW-LHRNRFSQFCWLFASFSGADLLKMSRDDLVQV----------CGPADGIR 357

  Fly  1229 ---MKRGRMTPPTSERVMLYVRQENEE------------------VYTPLHVVPPTTIGLLNAIE 1272
               ..:||...|   ::.:||.||.|:                  ||..:.:...||:.|...|.
  Rat   358 LFNAIKGRNVRP---KMTIYVCQELEQNQLPLPQKHDENGDNSLCVYHAIFLEELTTLELTEKIA 419

  Fly  1273 NKYKISTTSINNIYRTNKKGITAKIDDDMISFYCNEDIFLLEVQQIE-DDLYDVTL 1327
            :.|.|....|:.:||....||...:.::|:..:.:|..|:|...:.| :|.|.:.|
  Rat   420 SLYSIPPQHIHRVYRQGPAGIHVVVSNEMVQNFQDESCFILSTLKAESNDGYHIIL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grh	NP_476845.2	CP2	903..1089	CDD:461338	65/199 (33%)
Tfcp2l1	NP_001100640.1	CP2	35..237	CDD:461338	65/205 (32%)
		SAM_LBP9	310..376	CDD:188989	12/79 (15%)