Protein Alignment grh and grh-1

DIOPT Version :10

• Sequence 1: NP_476845.2
• Gene: grh / 37038
• FlyBaseID: FBgn0259211
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: NP_490837.2
• Gene: grh-1 / 190048
• WormBaseID: WBGene00001707
• Length: 563
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 234/624 - (37%)
• Similarity: 323/624 - (51%)
• Gaps: 165/624 - (26%)

  Fly   743 SVHHHQQQQQQQQQHQQ------------QQQQQQHHQQQQHHSQDG--KSNGGATPLYAKAIT- 792
            :|:::||....|.|:.|            |.:.:........:|..|  :|:....|.|.:.:|
 Worm    66 NVYNNQQILYAQTQNFQYPSTLLTNGSLAQTEWRGQQMDTSAYSNTGYSRSSTSQQPQYTQQVTE 130

  Fly   793 ---AAGLTVDLPSP-DSGIGTD--AITPRDQTNIQQSFDYTELCQPGTLIDANGSIPVSVNSIQQ 851
               .....||:||| |||||.|  .:.|::        ::......|::::.:          .:
 Worm   131 NERIVYKPVDMPSPVDSGIGGDISILNPKE--------EFFTSADGGSMLERS----------SE 177

  Fly   852 RTAVHGSQNSPTTSLVDTSTNGSTRSRPWHDFGRQNDADKIQIPKIFTNVGFRYHLESPISSSQR 916
            ||..|  ::||                             :.|||::.|:||:|.||:|||:|.|
 Worm   178 RTLSH--RDSP-----------------------------LVIPKLYNNLGFQYVLEAPISTSVR 211

  Fly   917 REDDRITYINKGQFYGITLEYVHDAEKPIKNTTVKSVIMLMFREEKSPEDEIKAWQFWHSRQHSV 981
            |:|||:||:||||||.::|||..|..|.:|:.||||.:|::|||:|:.|:|||.||.||:|||..
 Worm   212 RDDDRMTYVNKGQFYTVSLEYTPDLNKCLKSQTVKSQLMVVFREDKTYEEEIKTWQSWHARQHVS 276

  Fly   982 KQRILDADTKNSVGLVGCIEEVSHNAIAVYWNPLE-SSAKINIAVQCLSTDFSSQKGVKGLPLHV 1045
            |||||:.|:|||.|::|.|||:.:||:..||||.: |..:|:|||||||||||:|||||||||||
 Worm   277 KQRILEIDSKNSSGMIGQIEEIGNNAVQFYWNPSDPSGVRISIAVQCLSTDFSTQKGVKGLPLHV 341

  Fly  1046 QIDTFEDPRDTAVFHRGYCQIKVFCDKGAERKTRDEERRAAKRKM---TA----TGRKKLDELYH 1103
            ||||::...|...|||||||||||||||||||.|||::||.|||:   ||    .||||.|..||
 Worm   342 QIDTYDGENDKVPFHRGYCQIKVFCDKGAERKLRDEDKRAQKRKVQEYTAGALPGGRKKSDGEYH 406

  Fly  1104 PVTDRSEFYGMQDFAKPPVLFSPAEDMEKVGQLGIGAATGMTFNPLSNGNSNSNSHSSLQSFYGH 1168
            ...:|||||.|::..||..||...|:.|.                                   .
 Worm   407 DQCERSEFYHMRELDKPAALFIAPEEFEP-----------------------------------R 436

  Fly  1169 ETDSPDLKGASPFLLHGQKVATPTLKFHNHFPPDMQTDKKDHILDQNMLTSTPLTDFGP-PMKRG 1232
            ..||..|                                           |..:::..| |.||
 Worm   437 YVDSTSL-------------------------------------------SFDMSEIEPIPTKR- 457

  Fly  1233 RMTPPTSERVMLYVRQENEEVYTPLHVVPPTTIGLLNAIENKYKISTTSINNIYRTNKKGITAKI 1297
               |.||||:|||||:.:|::|.||||||.:..||..||.||:......::.:|:...||||.|:
 Worm   458 ---PRTSERIMLYVRKRDEQIYQPLHVVPASLSGLALAIANKFGADPDKMSGVYKRCAKGITVKV 519

  Fly  1298 DDDMISFYCNEDIFLLEVQQIEDDLYDVTLTEL----PN 1332
            ||:|:..|||||.|:::|:...|.....||.|:    ||
 Worm   520 DDEMLRLYCNEDTFIIDVEHATDGSTAATLIEVAPTNPN 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grh	NP_476845.2	CP2	903..1089	CDD:461338	121/186 (65%)
grh-1	NP_490837.2	CP2	198..385	CDD:461338	121/186 (65%)