Protein Alignment grh and grhl2b

DIOPT Version :9

• Sequence 1: NP_476845.2
• Gene: grh / 37038
• FlyBaseID: FBgn0259211
• Length: 1333
• Species: Drosophila melanogaster
• Sequence 2: XP_005159637.1
• Gene: grhl2b / 100034503
• ZFINID: ZDB-GENE-060503-719
• Length: 601
• Species: Danio rerio
• Alignment Length: 696
• Identity: 218/696 - (31%)
• Similarity: 322/696 - (46%)
• Gaps: 159/696 - (22%)

  Fly   683 EPSYY--REYFAPD-GQGGY----VPASTR---SLYGDVDVSVSQPGGVVTY-----EGRF---- 728
            |||::  |.|.:.| ....|    :.|:|:   |:.||.| |.:..|.:..|     :.|.
Zfish    17 EPSFHQRRPYTSEDEAWRSYLENPLTAATKAMMSINGDED-SAAALGLLYEYYKVPKDKRVPISK 80

  Fly   729 ---AGSVPPPATTTVLTS-------VHHHQQQQQQQQQHQQQQQQQQHHQQQQHHSQDGKSNGGA 783
               ....|...:|.|..|       |.:|.|..:....:.......|.::::|:....|:| |.|
Zfish    81 VVEMSDEPEKRSTPVGNSSQMEPETVDNHVQVLKSVPVNLSLNTDHQDNKREQYSVPAGES-GTA 144

  Fly   784 TPLYAKAITAAGLTVDLPSPDSGIGTDAITPRDQTNI----QQSFDYTELCQPGTLIDANGSIPV 844
            ..:.|:|.||..:|       || |.......:|..:    ..|||.:.:.......|.:.|.|.
Zfish   145 AVVKAEAHTAVFMT-------SG-GHYRTEGEEQMRVICEQTHSFDTSTINHSAYGKDDHRSSPE 201

  Fly   845 SVNSIQQRTAVHGSQNSPTTSLVDTSTNGSTRSRPWHDFGRQNDADKIQIPKIFTNVGFRYHLES 909
            |............|...|...:.|.|....|                           |:|.||:
Zfish   202 STYEDDSNEKYRSSSIGPDDFIFDQSHMLDT---------------------------FQYTLEA 239

  Fly   910 PISSSQRREDDRITYINKGQFYGITLEYVHDAEKPIKN--TTVKSVIMLMFREEKSPEDEIKAWQ 972
            ..|..|::.:..:||:||||||.|||... .|.|.:::  :.|:||:|::|.|:|:.::::|.|:
Zfish   240 SKSLRQKQGEGPMTYLNKGQFYAITLSET-SANKRLRHPISKVRSVVMVVFSEDKNRDEQLKYWK 303

  Fly   973 FWHSRQHSVKQRILD-ADTKNSVGLVGCIEEVSHNAIAVYWNPLESSAKINIAVQCLSTDFSSQK 1036
            :||||||:.|||:|| ||.|.|...:|.|||:::||::..|: |...|||.|.|.||||||||||
Zfish   304 YWHSRQHTAKQRVLDIADYKESFNTIGNIEEIAYNAVSFTWD-LNEEAKIFITVNCLSTDFSSQK 367

  Fly  1037 GVKGLPLHVQIDTFE-DPRDTAVFHRGYCQIKVFCDKGAERKTRDEERRAAKRKM--------TA 1092
            |||||||.:||||:. :.|.....||.|||||||||||||||.|||||:..::|.        |.
Zfish   368 GVKGLPLMIQIDTYSYNNRSNKPLHRAYCQIKVFCDKGAERKIRDEERKQNRKKTKGKDGGSGTV 432

  Fly  1093 TGRKKLDELYHPVTDRSEFYGMQDFAKPPVLFSP---AEDMEKVGQLGIGAATGMTFNPLSNGNS 1154
            |..||.|.        :.|..|.|....||||.|   ..::::.||:       ..||
Zfish   433 TVPKKCDS--------TLFKTMTDLDAQPVLFIPDVHFGNLQRAGQV-------FAFN------- 475

  Fly  1155 NSNSHSSLQSFYGHETDSPDLKGASPFLLHGQKVATPTLKFHNHFPPDMQTDKKDHILDQNMLTS 1219
                           |:..:.:|:                                :|.:.|..|
Zfish   476 ---------------TEEIECEGS--------------------------------VLVKRMFRS 493

  Fly  1220 TPLTDFGPPMKRGRMTPPTSERVMLYVRQENEEVYTPLHVVPPTTIGLLNAIENKYKISTTSINN 1284
            :. .||.||..: ::...|.:||:||||:|::||:..|.:..||..||::||..||.:....:..
Zfish   494 SE-EDFCPPPHK-QLREDTQKRVLLYVRKESDEVFDALMLRSPTVRGLMDAISEKYGVPIDRMAK 556

  Fly  1285 IYRTNKKGITAKIDDDMISFYCNEDIFLLEVQQIEDDLYDVTLTEL 1330
            ||:.:||||...:||::|..|.|||.|:|.::... |.|.:||||:
Zfish   557 IYKKSKKGILVNMDDNIIEHYSNEDTFILNIESYA-DAYKITLTEI 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grh	NP_476845.2	CP2	903..1089	CDD:282385	100/189 (53%)
grhl2b	XP_005159637.1	CP2	209..423	CDD:282385	106/242 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I3008
eggNOG	1	0.900	-	-		E1_KOG4091
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001445
OrthoInspector	1	1.000	-	-		otm24628
orthoMCL	1	0.900	-	-		OOG6_104596
Panther	1	1.100	-	-	O	PTHR11037
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X907
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.810