DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and grid2ip

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_012826769.3	Gene:	grid2ip / 780069	XenbaseID:	XB-GENE-981804	Length:	1275	Species:	Xenopus tropicalis

Alignment Length:	140	Identity:	30/140 - (21%)
Similarity:	50/140 - (35%)	Gaps:	28/140 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 GEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKAR 192
            |:|..|:|     |.|..|.:....|||                    :.|....|..|.:|...
Frog   238 GDQSALKE-----KVFSLLKQYAQDRKV--------------------DTLANSLSMILTQESHH 277

  Fly   193 LIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQKFKTL 257
            |:. |.|.|..|::..  .|...:|::::|.....:..:...::......|.:.|.|.|.:...:
Frog   278 LLI-DNIRIFIPKKHR--QRFDNVVSQSLISKMCRSRSDRSNRLRRSRSEDHHERLLVSTRAAPI 339

  Fly   258 AQLQDNSNAG 267
            .|.||....|
Frog   340 PQSQDEGGRG 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	22/116 (19%)
grid2ip	XP_012826769.3	PDZ_signaling	49..109	CDD:238492
		PDZ_signaling	120..193	CDD:238492
		harmonin_N_like	225..301	CDD:416392	21/90 (23%)
		PDZ_signaling	368..443	CDD:238492
		HN_L-delphilin-R2_like	478..557	CDD:259821
		FH2	884..1252	CDD:396655
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000