DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and Rgs20

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001171266.1	Gene:	Rgs20 / 58175	MGIID:	1929866	Length:	372	Species:	Mus musculus

Alignment Length:	217	Identity:	113/217 - (52%)
Similarity:	146/217 - (67%)	Gaps:	33/217 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GGGSLGGVSPTVGGSVGILGSTSNVLQESNATTFQRPQSQKPCCFCWCCCCSCSWAKCLAIKNAD 111
            ||....|.:|:..|..|           |||           |||||||||:||   ||.::|.:
Mouse   172 GGSETQGPAPSQQGGRG-----------SNA-----------CCFCWCCCCTCS---CLTVRNQE 211

  Fly   112 ENAP------TKRDLVNAEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENIL 170
            :..|      .:.|:...|  :...|||||:.:|.:|||.||.:.|||..|:.|||:||||||:|
Mouse   212 DQRPQRASHEIRTDIPACE--ESPTPTLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENML 274

  Fly   171 FWLACEDLKKENSPELVEEKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQ 235
            ||:|||:||:|.:...:|||||:|||||||||||:||||||||||::||||::|:.|.||:||:|
Mouse   275 FWMACEELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQ 339

  Fly   236 IYTLMHRDSYPRFLNSQKFKTL 257
            |||||||||||||:||..:|.|
Mouse   340 IYTLMHRDSYPRFMNSTVYKDL 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	80/116 (69%)
Rgs20	NP_001171266.1	RGS	205..360	CDD:295367	90/156 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3487
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3409
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47786
OrthoDB	1	1.010	-	-		D1409647at2759
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	1	1.000	-	-		otm43970
orthoMCL	1	0.900	-	-		OOG6_103880
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3135
SonicParanoid	1	1.000	-	-		X1014
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.770