DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and axin1

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_009297983.1	Gene:	axin1 / 57931	ZFINID:	ZDB-GENE-000403-1	Length:	871	Species:	Danio rerio

Alignment Length:	160	Identity:	46/160 - (28%)
Similarity:	79/160 - (49%)	Gaps:	13/160 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 AKCLAIKN-ADENAPTKRDLVNAEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFS 165
            :|..::|| |....|.:.||......:|..........|.:|...|:....|..:|:.||:.|..
Zfish    51 SKSDSLKNEASIATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGIHLFRTFLKQEEC 115

  Fly   166 EENILFWLACEDLKKE---NSPELVEEKARLIYEDYI----SILSPREV--SLDSRVREIVNRNM 221
            .:.:.||.||...:|:   :..|.:.:.|:.||:.||    .|:| |::  :..|.:::.|.:..
Zfish   116 ADMLDFWFACSGFRKQEANDGNEKMLKLAKAIYKKYILDNNGIVS-RQIKPATKSFIKDCVMKLH 179

  Fly   222 IEPTTHTFDEAQIQIYTLMHRDSYPRFLNS 251
            |:|.  .||:||.:|.|:|..::||.||.|
Zfish   180 IDPA--MFDQAQTEIQTMMEENTYPLFLKS 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	38/122 (31%)
axin1	XP_009297983.1	Axin_TNKS_binding	15..84	CDD:211424	8/32 (25%)
		RGS_Axin	93..212	CDD:188662	36/118 (31%)
		DUF507	368..>427	CDD:321349
		Axin_b-cat_bind	469..504	CDD:312391
		DIX	791..866	CDD:307085
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910