DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and rgs7a

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_021322815.1	Gene:	rgs7a / 436814	ZFINID:	ZDB-GENE-040718-276	Length:	487	Species:	Danio rerio

Alignment Length:	146	Identity:	52/146 - (35%)
Similarity:	86/146 - (58%)	Gaps:	3/146 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 EQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKARL 193
            ::|....:|.||...|:::|...||:.|..||.||||.||:.||||.::||:....| |..:.:.
Zfish   320 KEPGQTRVRRWGFGIDEVLKDPVGREQFLKFLESEFSSENLRFWLAVQELKRRPIRE-VPTRVQE 383

  Fly   194 IYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQKFKTLA 258
            |:|::::..:|..:::||:..:...:|:.:|..:.|::||..||.||..|||.||:.|..::.|
Zfish   384 IWEEFLAAGAPSAINVDSKSYDKTTQNVKDPGRYAFEDAQEHIYKLMKSDSYSRFIRSCAYQEL- 447

  Fly   259 QLQDNSNAGSKADSPT 274
             ||....:||..|..|
Zfish   448 -LQAKKKSGSIQDRRT 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	43/116 (37%)
rgs7a	XP_021322815.1	DEP_RGS7-like	29..116	CDD:239897
		GGL	256..316	CDD:128520
		RGS_RGS7	326..446	CDD:188692	44/120 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810