DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and rgs20

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_005163483.1	Gene:	rgs20 / 436704	ZFINID:	ZDB-GENE-040718-128	Length:	297	Species:	Danio rerio

Alignment Length:	249	Identity:	127/249 - (51%)
Similarity:	163/249 - (65%)	Gaps:	27/249 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ANNSGNNGNGNGNGGGGGVVGGGGSLGGVS--PTVGGSVGILGSTSNVLQESNATTFQRPQSQKP 88
            ||.|..|.:.|.|       ...||...:|  |.....:.:.....:|.|||.|.|....|:::|
Zfish    47 ANGSYENEDENEN-------TEDGSKDPISFQPMGSERMEMRKRQMSVQQESVAGTTAPAQNEQP 104

  Fly    89 ---------CCFCWCCCCSCSWAKCLAIKNADENAPTKRDLV------NAEFLDGEQPTLEEIRS 138
                     ||||||||||||   ||.::|.|.:...:|...      :|:|.:..:||.|||..
Zfish   105 GQGNRASNACCFCWCCCCSCS---CLTVRNEDRDERNRRASYDFKADGDADFEESPKPTAEEICL 166

  Fly   139 WGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKARLIYEDYISILS 203
            ||:||||||...:||..|:.|||:||||||:|||||||:.:||.:..::|||||:||||||||||
Zfish   167 WGQSFDKLMNCPSGRSAFRQFLRTEFSEENMLFWLACEEFRKEANKSVIEEKARIIYEDYISILS 231

  Fly   204 PREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQKFKTL 257
            |:||||||||||::||||:|||:||||:||:||||||.|||||||:||..:|.|
Zfish   232 PKEVSLDSRVREVINRNMLEPTSHTFDDAQLQIYTLMQRDSYPRFMNSPVYKNL 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	83/116 (72%)
rgs20	XP_005163483.1	RGS_RGS20	127..284	CDD:188700	94/156 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	181	1.000	Domainoid score	I3424
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	241	1.000	Inparanoid score	I3309
OMA	1	1.010	-	-		QHG47786
OrthoDB	1	1.010	-	-		D1409647at2759
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	1	1.000	-	-		otm26372
orthoMCL	1	0.900	-	-		OOG6_103880
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3135
SonicParanoid	1	1.000	-	-		X1014
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910