DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and Rgs9

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_035398.2	Gene:	Rgs9 / 19739	MGIID:	1338824	Length:	675	Species:	Mus musculus

Alignment Length:	137	Identity:	51/137 - (37%)
Similarity:	82/137 - (59%)	Gaps:	3/137 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 VNAEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPE 185
            :||:.:  |.||...:..|..:|.:|::...||:.||.||:.|||.||:.||.||||||..:..:
Mouse   280 LNAKLV--EIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSK 342

  Fly   186 LVEEKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLN 250
             |:|||..||:.:::..:.|.:::|.:..:|..:.:..|..:..|.||..||.||.:|||.|:|.
Mouse   343 -VKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLK 406

  Fly   251 SQKFKTL 257
            |..:|.:
Mouse   407 SPIYKEM 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	45/116 (39%)
Rgs9	NP_035398.2	DEP_RGS7-like	22..109	CDD:239897
		GGL	219..280	CDD:128520	51/137 (37%)
		RGS_RGS9	292..412	CDD:188693	45/120 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..571
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	637..662
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810