DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and eat-16

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_740904.1	Gene:	eat-16 / 172823	WormBaseID:	WBGene00001145	Length:	473	Species:	Caenorhabditis elegans

Alignment Length:	197	Identity:	64/197 - (32%)
Similarity:	98/197 - (49%)	Gaps:	39/197 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 PQSQKPCCFCWCCCCSCSWAKCLAIKNADENAPTKRDLVNAEFLDGEQPTLEEIRSWGKSFDKLM 147
            ||...|    |....:..|           |.||  |..:||.     ||.:.::.||.|..:|:
Worm   250 PQPSNP----WISDEASFW-----------NQPT--DTSSAEI-----PTEKRVKRWGLSVQELV 292

  Fly   148 KSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKARLIYEDYISILSPREVSLDSR 212
            |...||:|.:.||.||||.|||.||:|.:|||...: |.:.:||..|.|::::..:|.:|::|:|
Worm   293 KDPIGRQVLETFLESEFSSENIRFWIAIQDLKYAPN-EQIYQKAERIREEFLAQGAPAQVNVDNR 356

  Fly   213 VREIVNRNMIEPTTHTFDEAQIQ---------IYTLMHRDSYPRFLNSQKFK---TLAQLQDNSN 265
            ..:    ..:|..:...|.:|::         ::|||.:||||||:.||.:|   |.||......
Worm   357 TLD----QTLECISKAKDASQMRFAFYHSEEHVFTLMAKDSYPRFVRSQIYKAVLTAAQQHGTKR 417

  Fly   266 AG 267
            .|
Worm   418 LG 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	47/128 (37%)
eat-16	NP_740904.1	DEP_RGS7-like	18..94	CDD:239897
		GGL	204..266	CDD:128520	5/30 (17%)
		RGS_R7-like	280..405	CDD:188660	46/129 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910