DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and axin1

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_002935881.2	Gene:	axin1 / 100498631	XenbaseID:	XB-GENE-486781	Length:	877	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	68/249 - (27%)
Similarity:	104/249 - (41%)	Gaps:	44/249 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VGGGGSLGGVSPTVGGSVGILGSTSNVLQESNATTFQRPQSQKPCCFCWCCCCSCSWAKCLAIKN 109
            :||..:.....|.|.|..|.|           .||.|||.|.           |....|...|||
Frog    12 LGGSFTEDAPRPPVPGEEGEL-----------ITTDQRPFSH-----------SYYSLKNDGIKN 54

  Fly   110 ADENA-PTKRDLVNAEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWL 173
            ....| |.:.||......:|..........|.:|...|:....|..:|:.||:.|...:.:.||.
Frog    55 ETSTATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGINLFRTFLQQENCADLLDFWF 119

  Fly   174 ACEDLKK-ENSPELVEEK---ARLIYEDYI----SILSPREV--SLDSRVREIVNRNMIEPTTHT 228
            ||...:| |.:...||::   |:.||:.||    .|:| |::  :..|.:::.|.|..|:|.  .
Frog   120 ACSGFRKLEPNDSKVEKRLKLAKAIYKKYILDSNGIVS-RQIKPATKSFIKDCVLRQQIDPA--M 181

  Fly   229 FDEAQIQIYTLMHRDSYPRFLNSQ---KFKTLA-----QLQDNSNAGSKADSPT 274
            ||:||.:|.::|..::||.||.|.   ::.|:.     ...|.|:|......|:
Frog   182 FDQAQTEIQSMMEDNTYPVFLKSDTYLEYTTIGGESPKNYSDQSSASGTGKGPS 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	40/129 (31%)
axin1	XP_002935881.2	Axin_TNKS_binding	11..80	CDD:211424	23/89 (26%)
		RGS_Axin	89..209	CDD:188662	38/122 (31%)
		Axin_b-cat_bind	467..503	CDD:400956
		DIX	797..874	CDD:395628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910