DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and rgs8

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_002937412.1	Gene:	rgs8 / 100488999	XenbaseID:	XB-GENE-990044	Length:	216	Species:	Xenopus tropicalis

Alignment Length:	245	Identity:	76/245 - (31%)
Similarity:	123/245 - (50%)	Gaps:	43/245 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RLRGMTASSQQSAANNSGNNGNGNGNGGGGGVVGGGGSLGGVSPTVGGSVGILGSTSNVLQESNA 77
            :||.::.|....:|:.......|:|.|......|.         .:|.|.||....|.:.|:|:
Frog     6 KLRSLSLSCPTRSASEMDAALGGHGTGKPARPCGS---------NLGRSRGIRTHLSCLSQKSD- 60

  Fly    78 TTFQRPQSQKPCCFCWCCCCSCSWAKCLAIKNADENAPTKRDLVNAEFLDGEQPTLEEIRSWGKS 142
                                  |::...:::...:::...:.|           |.:|.|.|.:|
Frog    61 ----------------------SFSDFTSLQYDSKHSQALKRL-----------TPDEARRWARS 92

  Fly   143 FDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKARLIYEDYISILSPREV 207
            ||.|:....||.:|:.||::||||||:.||:|||:.:|..|...:..||..|::::|.:.:||||
Frog    93 FDLLLSHKYGRTMFRAFLQTEFSEENLEFWVACEEYRKTRSLNKLPAKAHHIFQEFIDVQAPREV 157

  Fly   208 SLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQKFKTL 257
            :||...||:..||::.||...||.||::|::||.||||||||.|:.:..|
Frog   158 NLDYPTRELTKRNLLHPTLSCFDLAQLRIHSLMERDSYPRFLRSKMYNDL 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	55/116 (47%)
rgs8	XP_002937412.1	RGS	82..206	CDD:383028	58/123 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910