DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and rgs20

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001121502.1	Gene:	rgs20 / 100158614	XenbaseID:	XB-GENE-976969	Length:	218	Species:	Xenopus tropicalis

Alignment Length:	211	Identity:	123/211 - (58%)
Similarity:	154/211 - (72%)	Gaps:	18/211 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 NVLQES-NATTFQR---PQSQKPCCFCWCCCCSCSWAKCLAIKNADENAPTKRD--------LVN 122
            :|.||: :||..|:   .:....||||||||||||   ||.::|.|:.. |:|.        :.|
Frog    14 SVHQEAVSATQAQQGVGNRGSNACCFCWCCCCSCS---CLTVRNQDDER-TRRSSNEIRGHGIPN 74

  Fly   123 AEFLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELV 187
            .|  :...||||::.|||:||||||.:.|||..|:.|||:||||||:|||:|||:||||.|..::
Frog    75 WE--ESPSPTLEDVYSWGQSFDKLMTTPAGRNAFREFLRTEFSEENMLFWMACEELKKEASKNVI 137

  Fly   188 EEKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQ 252
            |||||||||||||||||:||||||||||::||||:||:..|||:||:||||||||||||||:||.
Frog   138 EEKARLIYEDYISILSPKEVSLDSRVREVINRNMLEPSQRTFDDAQLQIYTLMHRDSYPRFMNSA 202

  Fly   253 KFKTLAQLQDNSNAGS 268
            .:|.|.|....|.|.|
Frog   203 IYKNLLQTLSESPADS 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	86/116 (74%)
rgs20	NP_001121502.1	RGS_RGS20	46..206	CDD:188700	102/165 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	183	1.000	Domainoid score	I3375
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	241	1.000	Inparanoid score	I3248
OMA	1	1.010	-	-		QHG47786
OrthoDB	1	1.010	-	-		D1409647at2759
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	1	1.000	-	-		otm49145
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3135
SonicParanoid	1	1.000	-	-		X1014
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.010