DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dhit and rgs19

DIOPT Version :9

Sequence 1:	NP_611271.3	Gene:	Dhit / 37037	FlyBaseID:	FBgn0028743	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001120125.1	Gene:	rgs19 / 100145150	XenbaseID:	XB-GENE-5736048	Length:	220	Species:	Xenopus tropicalis

Alignment Length:	211	Identity:	123/211 - (58%)
Similarity:	151/211 - (71%)	Gaps:	23/211 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LQESNATTFQRPQSQK-----PCCFCWCCCCSCSWAKCLAIKNADEN------APTKRDLV-NAE 124
            |.||..:.:.|.|..:     ||||||||||||||       |.|.|      ..||.::| :.|
Frog    21 LSESPMSRYDRNQPTRNHRSNPCCFCWCCCCSCSW-------NEDRNRRRRLSRDTKLEIVPHCE 78

  Fly   125 FLDGEQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEE 189
            ..  .:|:.||||||..||:|||||.|||.||:.|||:|:||||:|||||||:||||.....|||
Frog    79 VC--SKPSSEEIRSWAGSFEKLMKSPAGRNVFREFLRTEYSEENMLFWLACEELKKEYCRPSVEE 141

  Fly   190 KARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNSQKF 254
            |||.|||||||||||:||||||||||::||.|.:|:.||||:||:||||||||||:||||||..:
Frog   142 KARGIYEDYISILSPKEVSLDSRVREMINRRMQDPSPHTFDDAQLQIYTLMHRDSFPRFLNSGIY 206

  Fly   255 KTLAQLQDNSNAGSKA 270
            |:|  ||:.|.:.|::
Frog   207 KSL--LQNISRSSSES 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhit	NP_611271.3	RGS_RZ-like	139..256	CDD:188673	85/116 (73%)
rgs19	NP_001120125.1	RGS	91..208	CDD:295367	85/116 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	183	1.000	Domainoid score	I3375
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	241	1.000	Inparanoid score	I3248
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1409647at2759
OrthoFinder	1	1.000	-	-		FOG0000119
OrthoInspector	1	1.000	-	-		otm49145
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1014
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060