DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc10 and UBE2L3

DIOPT Version :9

Sequence 1:	NP_477414.1	Gene:	Ubc10 / 37035	FlyBaseID:	FBgn0026316	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	NP_001243284.1	Gene:	UBE2L3 / 7332	HGNCID:	12488	Length:	212	Species:	Homo sapiens

Alignment Length:	146	Identity:	108/146 - (73%)
Similarity:	131/146 - (89%)	Gaps:	0/146 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KELSDLQGNALKSFRDIKADDDNLLRWTGLIVPDNPPYNKGAFRIEINFPAEYPFKPPKINFKTR 73
            :||.:::...:|:||:|:.|:.|||.|.||||||||||:|||||||||||||||||||||.|||:
Human    67 EELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTK 131

  Fly    74 IYHPNIDEKGQVCLPIISTENWKPATRTDQVVQALVDLINDPEPEHPLRAELAEEFLKDRKKFVK 138
            |||||||||||||||:||.|||||||:||||:|:|:.|:|||:|||||||:||||:.||||||.|
Human   132 IYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCK 196

  Fly   139 NAEDYTKKHSEKRPAD 154
            |||::|||:.||||.|
Human   197 NAEEFTKKYGEKRPVD 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc10	NP_477414.1	UQ_con	6..144	CDD:395127	100/134 (75%)
UBE2L3	NP_001243284.1	COG5078	67..208	CDD:227410	103/140 (74%)
UBE2L3	NP_001243284.1	UBCc	67..207	CDD:214562	103/139 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	232	1.000	Domainoid score	I2425
eggNOG	1	0.900	-	-		E2759_KOG0422
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3195
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51868
OrthoDB	1	1.010	-	-		D1420213at2759
OrthoFinder	1	1.000	-	-		FOG0002530
OrthoInspector	1	1.000	-	-		otm41830
orthoMCL	1	0.900	-	-		OOG6_106294
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3871
SonicParanoid	1	1.000	-	-		X2225
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870