DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubc10 and UBE2Z

DIOPT Version :9

Sequence 1:	NP_477414.1	Gene:	Ubc10 / 37035	FlyBaseID:	FBgn0026316	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	NP_075567.2	Gene:	UBE2Z / 65264	HGNCID:	25847	Length:	354	Species:	Homo sapiens

Alignment Length:	146	Identity:	35/146 - (23%)
Similarity:	63/146 - (43%)	Gaps:	34/146 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TAPR---RLRKELSDLQGNALKSFRD------IKADDDNLLRWTGLIV-PDNPPYNKGAFRIEIN 56
            |||:   |:::::..:       :::      :..|..::.:...||. |.:.||..|.|.....
Human    96 TAPQCLLRIKRDIMSI-------YKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFR 153

  Fly    57 FPAEYPFKPPKINFKTR-----IYHPNIDEKGQVCLPIIST---ENWKPATRTDQVVQALVDLI- 112
            .|.:||..||::...|.     .::||....|:|||.|:.|   ..|.||.....|:.::..|:
Human   154 CPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMT 218

  Fly   113 -----NDP---EPEHP 120
                 |:|   :..||
Human   219 ENPYHNEPGFEQERHP 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubc10	NP_477414.1	UQ_con	6..144	CDD:395127	32/139 (23%)
UBE2Z	NP_075567.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		UBCc	103..221	CDD:238117	28/124 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	332..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910