Protein Alignment aft and Cmtr2

DIOPT Version :10

• Sequence 1: NP_477413.1
• Gene: aft / 37034
• FlyBaseID: FBgn0026309
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_666327.2
• Gene: Cmtr2 / 234728
• MGIID: 2384580
• Length: 767
• Species: Mus musculus
• Alignment Length: 776
• Identity: 238/776 - (30%)
• Similarity: 350/776 - (45%)
• Gaps: 145/776 - (18%)

  Fly     4 RSSPQGKPHPMTDYQSIRPSEVEQLFEKKFHYQKPKGNKSWQLPPPDQALFSEFYQFEALQGLRE 68
            |..|..:|..:..:.....::|.:||.|.|.|:||..|: ||||.|.::......:|.||..|:.
Mouse     5 RKLPARQPACLETFSPDVLNDVSELFAKSFSYRKPLDNE-WQLPAPTESFSCGHLEFRALLDLKN 68

  Fly    69 QLNAVKSKLNDYGVQEWSAHTNRRDPSGEVSWRLKNDTKAEFVTVAWCKLFECLHRYPLVTKPA- 132
            .||.||:.|:|..:.||..||...:.:|::...:|....||..|.||||..|.|..:||:.:.|
Mouse    69 SLNEVKNLLSDKKLDEWHRHTAFTNKAGKIISHVKKAVNAELCTQAWCKFQEILCSFPLIPQEAF 133

  Fly   133 ----VNSMHLCEAPGAFIASLNHYLHSKYEKDEIKWRWRSTTLNPYYEGNAINQMISDDRFIVHT 193
                :||:|||||||||||||||||  |..:...:|.|.:.:||||:|.|...:||:|||.:.:|
Mouse   134 QSGRLNSLHLCEAPGAFIASLNHYL--KSHRFPCEWSWVANSLNPYHEANDNLRMITDDRLMANT 196

  Fly   194 LDNWFFHKDLTGNLLDVANIDHLVERCEVEFQGQVDLVTADGSIDCAAQPDCQEEIVVRLFFAEV 258
            |..|:|..|.||:::.:..:..|.:  .:.....:.|||||||.||...|..||.:|..|.:.|.
Mouse   197 LHCWYFGPDNTGDIMTLKYLTGLQD--FLSGMSPIHLVTADGSFDCQGNPGEQEALVSSLHYCEA 259

  Fly   259 LSALRILSSGGNFLVKMFTLFEACSVSLLYTLNCIFEEVHIFKPATSKRGNSEVYVICLNY---N 320
            ::||..|..||:|::|||||||.|||:|:|.|||.|::||:|||||||.|||||||:||.|   .
Mouse   260 VTALITLGDGGSFVLKMFTLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLRYKGRE 324

  Fly   321 KDHPDLPRLLEEIKSKLAQPNDTLVMPLFAKFQIPHDFLMQHEIACRMYMKLQTDAIEGSIYAYE 385
            ...|.|.|::....:::.:      ..||....||..||.:||..|..:.:.|.:.|..:|..:|
Mouse   325 AVQPLLSRMVLNFGTEMTR------KALFPHHVIPKSFLERHEECCTFFHRYQLETISENIRLFE 383

  Fly   386 SNDRHYLRHLHHLRSLVANTYYSLYKVKPLEDSLCIVDK-----EATSKALGFQVPVYGGSYTER 445
            |........|::||......:...:::|||..:..:|.|     ...:|..| |...|..:|.||
Mouse   384 SMGTGEQERLNNLRDCAVQYFMQKFQLKPLSRNHWLVKKSNIGCSMNTKWFG-QRNKYFKTYNER 447

  Fly   446 ESLK----------------------------------------------HGDLLKQIYCLRREF 464
            :.::                                              .|..|.::.|.....
Mouse   448 KMMETLSWKDKVAKGYFNSWAEEHTVYHPGQNSLLEGTASSLEYQSWQVLEGKKLPKVKCSPFCD 512

  Fly   465 NQLEKCLNNRTPYSYVKNRTAPLNLHISRGAPVQSLQS----SMFASEPIL--ILRLR--ILDTF 521
            .::.|.||.....|        |...:|..|.|.|.|.    .:|:.|.:|  :|||.  :.|..
Mouse   513 GEILKTLNEAIEKS--------LGEALSVDAKVSSKQQYRCCPVFSEESVLSELLRLTKCLPDEQ 569

  Fly   522 ELDPVWQSAP-KCQL-ESKTLCYL---PPTEDEAFHT----------------AQQRFFID-LLE 564
            ..:|   |.| ||.| .|..:|.|   .|.|.:...:                |.|..|:| ||.
Mouse   570 GAEP---SGPVKCLLVGSPAVCDLQMPAPLEIQLVESVELTAFSCSLLHDGDPAYQHLFLDCLLH 631

  Fly   565 EVKKLKPDSIV-------FHKFL----FLTHYAASLLLF--------------LIESVYQ---DC 601
            .:::|....::       |.:|:    |:.|.....:.|              |:...||   |.
Mouse   632 SLRRLHRGDVMVLPILSCFTRFMAGLTFVLHGCFRFITFSCPTSLEPLRTCAVLLCIGYQNLPDA 696

  Fly   602 CFNSNQAQTLTLSKLKDTANSALEQVLELLKDE---QAGAIHSLLDIKELQKNQFSKALIQ 659
            .|...|.....||||...  ||..|:|:.|..|   |...:..|.|:......:....:||
Mouse   697 VFQFLQNVHDLLSKLLHP--SAPRQILQFLPMEALLQGTLLDFLWDLNAAIAKRHLHLIIQ 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aft	NP_477413.1	FtsJ	110..319	CDD:426399	106/213 (50%)
Cmtr2	NP_666327.2	FtsJ	114..320	CDD:426399	105/209 (50%)