Protein Alignment aft and Y40D12A.1

DIOPT Version :9

• Sequence 1: NP_477413.1
• Gene: aft / 37034
• FlyBaseID: FBgn0026309
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_498461.3
• Gene: Y40D12A.1 / 182563
• WormBaseID: WBGene00021502
• Length: 635
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 130/613 - (21%)
• Similarity: 232/613 - (37%)
• Gaps: 196/613 - (31%)

  Fly    79 DYGVQEWSAHTNRRDPSGEVSWRLKN--------DTKAEFVT----------------VAWCKLF 119
            ||   |:|..|||...:.....::|:        |...:|..                :..|::|
 Worm    48 DY---EFSKQTNRLTQAAMEIRKIKDKDLYDQHTDMMHDFARNPRILQNYFICKNKAFLKLCEIF 109

  Fly   120 ECLHRYPLVTKPAVNSMHLCEAPGAFIASLN-HYLHSKYEKDEIK-WRWRSTTLNPYYEGNAINQ 182
            | :.::.:....:::|.||||.||.||.::: ..:.|:.:.:|:. |:|.:.|||||:|..:...
 Worm   110 E-VFKFDIFEGSSISSFHLCEGPGYFIEAVHVALMRSRGKNEEMSYWKWGANTLNPYFENRSCFD 173

  Fly   183 MISDDRFIVHTLDNWFFHKDLTGNLLDVANIDHLVERCEVEFQGQVDLVTADGSIDCAAQPDCQE 247
            .:.||..|..|:|.|:|.....|: ::....::|:::   :..|..||||||||.:...:....|
 Worm   174 KLIDDSHIRPTMDQWYFGPSDDGD-IEKFTEEYLIKQ---KLAGTFDLVTADGSTNTQGKEGEIE 234

  Fly   248 EIVVRLFFAEVLSALRILSSGGNFLVKMFTLFEACSVSLLYTLNCI---FEEVHIFKPATSKRGN 309
            .||..|..|||..||::|...|..::|.:..   |:.|....:|.:   |..:...||..|:.|:
 Worm   235 SIVSSLISAEVEVALKLLRRNGRLILKTYRF---CAKSTRDVMNLLADNFSSIKAIKPMASRPGS 296

  Fly   310 SEVYVICLNYNKDHPDLPRLLEEIKSKLAQPNDTLVMPLFAKFQIPHDFLMQHEIACRMYMKLQT 374
            ||.|::|..:...                                     |..:|:    |.||.
 Worm   297 SERYIVCDGFGGS-------------------------------------MNMDIS----MLLQC 320

  Fly   375 DAIEGSIYAYESNDR---HYLRHLHHLRSLVANTYYSLYKVKPLEDSLCIVDKEATSKALGFQVP 436
            |    ..:.|:..||   |....:.|.|..:.:.:.|..|.        :.||..|:::
 Worm   321 D----EFFVYKQIDRIELHLKTFIEHHRMYLKDNWNSFLKT--------MKDKSFTAES------ 367

  Fly   437 VYGGSYTERESLKHGDLLKQIYCLRREFNQLEKCLNNRTPYSYVK-------NRTAPLNLHIS-- 492
                               :.:|  ||...:....::|:...:::       .|..|.:|.||
 Worm   368 -------------------RYFC--RELQSMFPSGSSRSSSPWMRLYGHNLIRRNNPEDLKISIN 411

  Fly   493 -------------RGAPVQSLQSSMFASEPILI---LRLRILDTFELDPVWQSAPKCQLESKTLC 541
                         :...|:.:.:.:...|.||.   ::||.:|:..:||:   |.|..|...:
 Worm   412 RYILTADIFDPDYQKLDVEQIVARIMDQEEILTTSDIQLRTIDSLFVDPI---ALKQMLSHNS-- 471

  Fly   542 YLPPTEDEAFHTAQQRFFIDLLEEVK-KLKPDSIVFHKFLFLTHYAASLLLFLIESVYQDCCFNS 605
                           :.:.||.|:|. |...|...:.|     :::                 ||
 Worm   472 ---------------KIYYDLFEKVSTKNSADECDWRK-----NFS-----------------NS 499

  Fly   606 NQAQTLTLSKLKDTANSALEQVLELLKD 633
            |:..||.|    || |..:|.:|..:.:
 Worm   500 NRNYTLKL----DT-NVTIEHILAAISE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aft	NP_477413.1	FtsJ	110..319	CDD:279986	65/229 (28%)
Y40D12A.1	NP_498461.3	FtsJ	97..306	CDD:376603	64/216 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165901
Domainoid	1	1.000	107	1.000	Domainoid score	I4093
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1327262at2759
OrthoFinder	1	1.000	-	-		FOG0007380
OrthoInspector	1	1.000	-	-		oto18218
orthoMCL	1	0.900	-	-		OOG6_105981
Panther	1	1.100	-	-	LDO	PTHR16121
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5504
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.850