DRSC/TRiP Functional Genomics Resources

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Protein Alignment fab1 and zfyve28

DIOPT Version :9

Sequence 1:NP_611269.1 Gene:fab1 / 37033 FlyBaseID:FBgn0028741 Length:1809 Species:Drosophila melanogaster
Sequence 2:NP_001072498.1 Gene:zfyve28 / 779953 XenbaseID:XB-GENE-1219057 Length:951 Species:Xenopus tropicalis


Alignment Length:255 Identity:61/255 - (23%)
Similarity:100/255 - (39%) Gaps:66/255 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 NQSYNTVNDISSGSSSSSSTQPVQVVGKSQFFSDSQTSTA----EIADVETSSQSSVRPQPPTTL 108
            :.|.:.:.|.:..|.|||..:.|.|...|....||.:|.:    :..:::.:.|::         
 Frog   717 SSSQDGLRDSALSSISSSDYESVSVTTCSLSSIDSLSSCSSDDIDQEEIQLALQAA--------- 772

  Fly   109 SIRTNSETRGTSTSSNTAAED-----SETSDRVETLPLPTSEANQGRTVSNVLKHISNIVATKNN 168
            .|.:..:.|....|||.....     |..:|:::|        |....:.::||.:..::|||..
 Frog   773 KIASRQKIRSRFHSSNDLIHRLFVCISGVADQLQT--------NYASDLRSILKTLFEVMATKQE 829

  Fly   169 ND-----------LRN---------------------YKDTELQ--RFWMPDSKAKECYDCSQKF 199
            .|           ||:                     .:|.|.:  ..|:||.....|..|...|
 Frog   830 TDDKGKQKKANQGLRSAALEDCALCQETITSSELAAKARDGEFEDPPDWVPDEVCSLCTACKAPF 894

  Fly   200 STFRRKHHCRLCGQIFCSKCCNQVVPGMIIRCDGDLK---VCNYCSKIVLTFLKSSSSEM 256
            :..|||||||.||:||||:|.:...|   :...|.:|   ||.:|....:|...|..:.|
 Frog   895 TVIRRKHHCRSCGKIFCSRCSSHSAP---LPRYGQMKPVRVCTHCYMFHVTPFYSDRAGM 951

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fab1NP_611269.1 FYVE_PIKfyve_Fab1 182..243 CDD:277264 26/63 (41%)
DEP 329..397 CDD:214489
Fab1_TCP 464..717 CDD:239450
PIPKc 1413..1797 CDD:295374
zfyve28NP_001072498.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 360..382
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 527..557
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 641..726 1/8 (13%)
FYVE_LST2 874..938 CDD:277270 26/66 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2108
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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