DRSC/TRiP Functional Genomics Resources

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Protein Alignment fab1 and zfyve28

DIOPT Version :9

Sequence 1:NP_611269.1 Gene:fab1 / 37033 FlyBaseID:FBgn0028741 Length:1809 Species:Drosophila melanogaster
Sequence 2:NP_001071191.1 Gene:zfyve28 / 777615 ZFINID:ZDB-GENE-061103-208 Length:969 Species:Danio rerio


Alignment Length:235 Identity:58/235 - (24%)
Similarity:92/235 - (39%) Gaps:66/235 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 SSSSSTQPVQVVGKSQFFSDSQTSTAEIADVETSSQSSVRPQPPTTLSIRT-------NSETRGT 119
            :|||...|:..|..|.....|.|:        .|..||..|.|.::|:..:       :.|.:..
Zfish   731 NSSSQESPLSSVPSSDIDGVSVTT--------CSLSSSYAPSPVSSLTTSSDMSEDLDHQEIQVA 787

  Fly   120 STSSNTAAEDS------ETSDRVETLPLPTS------EANQGRTVSNVLKHISNIVATKNN---- 168
            ..::..||.:.      .:||.:..|.:..|      :.|....:.::||.:..::|||.:    
Zfish   788 LQAAKLAAHNKIRSRFHSSSDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKTDQGDN 852

  Fly   169 --------------NDLRNYKDT----ELQ------RF-----WMPDSKAKECYDCSQKFSTFRR 204
                          .|....::|    ||.      :|     |:||.....|..|...|:..||
Zfish   853 EKPKKGPCLGSAVLEDCALCQETISSSELAAKAREGQFEDPPEWVPDEACNSCIACKAPFTVIRR 917

  Fly   205 KHHCRLCGQIFCSKCCNQVVPGMIIRCDGDLK---VCNYC 241
            |||||.||:||||:|.:...|   :...|.:|   ||.:|
Zfish   918 KHHCRSCGKIFCSRCSSHSAP---LPRYGQMKPVRVCTHC 954

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fab1NP_611269.1 FYVE_PIKfyve_Fab1 182..243 CDD:277264 27/68 (40%)
DEP 329..397 CDD:214489
Fab1_TCP 464..717 CDD:239450
PIPKc 1413..1797 CDD:295374
zfyve28NP_001071191.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 290..323
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 336..360
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 390..437
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..777 14/53 (26%)
FYVE_LST2 892..956 CDD:277270 26/66 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2108
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.030

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